Description

9-Benzyl-6-Oxa-9-Azaspiro[3.6]Decan-8-One is a high-purity, advanced pharmaceutical intermediate featuring a unique spirocyclic scaffold. This compound is of significant value for medicinal chemistry research and development, particularly in the synthesis of novel active pharmaceutical ingredients (APIs) targeting central nervous system and other therapeutic areas. It is primarily sought by R&D chemists and process development scientists in the pharmaceutical, biotechnology, and fine chemical industries for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel drug candidates, especially those requiring spirocyclic or bridged heterocyclic structures.
• Medicinal Chemistry Research: Used in hit-to-lead optimization and structure-activity relationship (SAR) studies to explore new chemical space.
• Process Chemistry Development: Serves as a critical intermediate for scaling up the production of target molecules under Good Manufacturing Practice (GMP) conditions.
• Academic Research: Employed in universities and research institutes for methodological studies in organic synthesis and heterocyclic chemistry.
• Contract Research and Manufacturing (CRAM): Supplied to organizations offering custom synthesis and development services for the global pharmaceutical market.

Basic Information

Product Name	9-Benzyl-6-Oxa-9-Azaspiro[3.6]Decan-8-One
CAS No.	1160245-66-8
Molecular Formula	C15H19NO2
Molecular Weight	245.32 g/mol
Synonyms	9-Benzyl-6-oxa-9-azaspiro[3.6]decan-8-one; 6-Oxa-9-azaspiro[3.6]decan-8-one, 9-benzyl-; 9-Benzyl-6-oxa-9-azaspiro[3.6]decane-8-one; 9-Benzyl-6-oxa-9-azaspiro[3.6]decan-8-on; 9-Benzyl-6-oxa-9-azaspiro[3.6]decan-8-one (CAS 1160245-66-8); Spirocyclic benzyl oxazaspirodecanone; Benzyl-protected oxa-azaspirodecanone intermediate.
EINECS	Contact for details

Quality Control

Our 9-Benzyl-6-Oxa-9-Azaspiro[3.6]Decan-8-One is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and MS, to ensure identity, purity, and consistency. We provide Certificates of Analysis (COA) with detailed specifications for every shipment, supporting your regulatory and R&D documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from incompatible materials such as strong acids and strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC/IR)	Conforms to reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 0.5%
Residual Solvents (GC)	Complies with ICH Q3C guidelines
Water Content (KF)	≤ 0.5% w/w

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.