Description

Spiro[1,3-Dioxolane-2,5'-1,4,6,7-Tetrahydroindazole] CAS NO 1160245-61-3 is a high-purity, advanced pharmaceutical intermediate characterized by its unique spirocyclic molecular architecture. This compound is of significant value in modern organic synthesis, serving as a critical building block for the development of novel, complex active pharmaceutical ingredients (APIs). It is primarily sought after by research institutions and manufacturers in the pharmaceutical and agrochemical sectors for applications in drug discovery and process chemistry.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders.
• Agrochemical Research: Used in the development of new pesticides and herbicides with specific modes of action.
• Organic Synthesis Building Block: Employed in academic and industrial R&D for constructing complex heterocyclic frameworks and spiro compounds.
• Medicinal Chemistry: Integral for structure-activity relationship (SAR) studies and lead optimization in drug discovery programs.
• Chemical Biology Probes: Serves as a scaffold for developing molecular probes to study biological pathways.
• Custom Synthesis: Available for contract manufacturing and custom synthesis projects requiring high-purity, specialized intermediates.

Basic Information

Product Name	Spiro[1,3-Dioxolane-2,5'-1,4,6,7-Tetrahydroindazole]
CAS No.	1160245-61-3
Molecular Formula	C10H12N2O2
Molecular Weight	192.22 g/mol
Synonyms	1,4,6,7-Tetrahydrospiro[indazole-5,2'-[1,3]dioxolane]; Spiro(1,3-dioxolane-2,5'-1,4,6,7-tetrahydroindazole); 1,4,6,7-Tetrahydro-5H-indazole-5-spiro-2'-(1',3'-dioxolane); 5H-Indazole-5,2'-[1,3]dioxolane, 1,4,6,7-tetrahydro-; 1160245-61-3
EINECS	Contact for details

Quality Control

Our Spiro[1,3-Dioxolane-2,5'-1,4,6,7-Tetrahydroindazole] is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure high purity and consistent identity. Certificates of Analysis (COA) detailing all specifications are provided with each shipment. We adhere to cGMP principles for pharmaceutical intermediates to support our clients' regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from incompatible materials such as strong acids, bases, and oxidizing agents. For long-term storage, consider an inert atmosphere to ensure optimal stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Residual Solvents (GC)	Meets ICH Q3C guidelines
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.