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1-(Benzyloxycarbonyl)-5-(Methoxycarbonyl)Piperidine-3-Carboxylic Acid CAS NO 1159982-68-9


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CAS No.:1159982-68-9

Grade:Pharmacy Grade

Content:99.9%

Brand:Customizable

Packaging:Customizable

Description

1-(Benzyloxycarbonyl)-5-(Methoxycarbonyl)Piperidine-3-Carboxylic Acid is a protected piperidine derivative that serves as a critical building block in advanced organic synthesis. This compound is valued for its role in constructing complex molecular architectures, particularly in pharmaceutical research and development. It is primarily sought by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and fine chemical industries for the synthesis of novel active ingredients and intermediates.

Application

  • Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly those targeting neurological and metabolic disorders.
  • Peptidomimetic Scaffold: Used to construct constrained peptide analogs and protease inhibitors due to its rigid piperidine core.
  • Agrochemical Synthesis: Serves as a building block for developing new active ingredients in crop protection products.
  • Chemical Biology Probes: Utilized in the development of tool compounds and molecular probes for target validation and pathway studies.
  • Custom Synthesis & Contract Manufacturing: A vital starting material for custom synthesis projects requiring specific chirality or functionalization.
  • Academic & Institutional Research: Employed in universities and research institutes for methodological development and exploring new chemical spaces.

Basic Information

Product Name 1-(Benzyloxycarbonyl)-5-(Methoxycarbonyl)Piperidine-3-Carboxylic Acid
CAS No. 1159982-68-9
Molecular Formula C16H19NO6
Molecular Weight 321.33 g/mol
Synonyms 5-(Methoxycarbonyl)-1-[(phenylmethoxy)carbonyl]piperidine-3-carboxylic acid; 1-Cbz-5-(COOMe)-piperidine-3-COOH; 1-(Benzyloxycarbonyl)-5-(methoxycarbonyl)-3-piperidinecarboxylic acid; 3-Piperidinecarboxylic acid, 1-[(phenylmethoxy)carbonyl]-5-(methoxycarbonyl)-; Z-5-(Methoxycarbonyl)piperidine-3-carboxylic acid; 1-N-Cbz-5-methyl piperidine-1,5,3-tricarboxylate; Piperidine-3-carboxylic acid, 1-(benzyloxycarbonyl)-5-(methoxycarbonyl)-
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Quality Control

Our 1-(Benzyloxycarbonyl)-5-(Methoxycarbonyl)Piperidine-3-Carboxylic Acid is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity for research and development applications. We provide comprehensive Certificates of Analysis (COA) with each batch, detailing purity, identity, and impurity profiles. Our quality management system supports compliance with cGMP and ISO standards for pharmaceutical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and should be handled under dry conditions to prevent degradation. Keep away from incompatible materials.

Specification

Item Specification
Appearance White to off-white crystalline powder
Identification (IR) Conforms to structure
Purity (HPLC) ≥ 97.0%
Water Content (KF) ≤ 1.0%
Residue on Ignition ≤ 0.1%
Heavy Metals ≤ 20 ppm
Single Unknown Impurity (HPLC) ≤ 0.5%
Total Impurities (HPLC) ≤ 3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.

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