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2,2,2-Trifluoro-1-[1-(2,2,2-Trifluoro-Acetyl)Piperidin-3-Yl]-Ethanone CAS NO 1159982-57-6


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CAS No.:1159982-57-6

Grade:Pharmacy Grade

Content:99.9%

Brand:Customizable

Packaging:Customizable

Description

2,2,2-Trifluoro-1-[1-(2,2,2-Trifluoro-Acetyl)Piperidin-3-Yl]-Ethanone is a high-purity, specialized fluorinated building block of significant interest in advanced organic synthesis. Its value lies in its unique molecular architecture, featuring two trifluoroacetyl groups attached to a piperidine ring, which is critical for modulating the physicochemical properties of target molecules. This compound is primarily needed by research and development teams in the pharmaceutical and agrochemical industries for the discovery and development of new active ingredients.

Application

  • Pharmaceutical Intermediate: Serves as a key synthon in the research and development of novel active pharmaceutical ingredients (APIs), particularly for introducing lipophilicity and metabolic stability.
  • Agrochemical Synthesis: Used in the creation of advanced herbicides, fungicides, and insecticides where the fluorine atoms enhance biological activity and environmental persistence.
  • Material Science Research: Employed in the synthesis of specialty polymers and advanced materials that require fluorinated components for specific thermal or chemical resistance properties.
  • Ligand and Catalyst Development: Acts as a precursor for complex ligands used in asymmetric catalysis and metal-organic frameworks (MOFs).
  • Fluorine Chemistry Studies: A valuable compound for academic and industrial research focused on the synthesis and reactivity of organofluorine molecules.

Basic Information

Product Name 2,2,2-Trifluoro-1-[1-(2,2,2-Trifluoro-Acetyl)Piperidin-3-Yl]-Ethanone
CAS No. 1159982-57-6
Molecular Formula C9H7F6NO2
Molecular Weight 275.15 g/mol
Synonyms 1,1'-(3-Piperidinyl)bis[2,2,2-trifluoroethanone]; 3,3'-Bis(trifluoroacetyl)piperidine; 1-(1-(2,2,2-Trifluoroacetyl)piperidin-3-yl)-2,2,2-trifluoroethan-1-one; 2,2,2-Trifluoro-1-[1-(2,2,2-trifluoroacetyl)-3-piperidinyl]ethanone; N-(2,2,2-Trifluoroacetyl)piperidine-3-carboxylic acid trifluoroacetyl derivative; 3-Piperidinebis(trifluoroethanone)
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Quality Control

Our 2,2,2-Trifluoro-1-[1-(2,2,2-Trifluoro-Acetyl)Piperidin-3-Yl]-Ethanone is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided and available upon request to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, containers should be kept in amber glass or opaque packaging during storage and handling.

Specification

Item Specification
Appearance White to off-white crystalline powder
Identification (IR) Conforms to structure
Identification (NMR) Conforms to structure
Purity (HPLC) ≥ 98.0%
Water Content (KF) ≤ 0.5%
Residue on Ignition ≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.

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