Description

3-Methylamino-Piperidine-1-Carboxylic Acid Benzyl Ester is a high-purity, advanced pharmaceutical intermediate with a protected amine and ester functionality. This compound matters for its critical role as a versatile building block in the synthesis of complex active pharmaceutical ingredients (APIs) and fine chemicals. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for constructing novel molecular architectures.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of piperidine-based drug candidates, including potential central nervous system (CNS) agents and enzyme inhibitors.
• Organic Synthesis Reagent: Serves as a protected amine synthon in multi-step synthetic routes, enabling selective reactions at other functional sites.
• Agrochemical Research: Used in the development of novel pesticides and herbicides that incorporate the piperidine scaffold for biological activity.
• Chemical Biology & Proteomics: Employed in the design and synthesis of molecular probes, enzyme substrates, or inhibitors for biochemical research.
• Custom Synthesis & Contract Manufacturing: A starting material for custom synthesis projects requiring specific chiral or functionalized piperidine derivatives.
• Academic & Institutional Research: Utilized in university and institutional labs for methodological development and exploring new chemical spaces.

Basic Information

Product Name	3-Methylamino-Piperidine-1-Carboxylic Acid Benzyl Ester
CAS No.	1159982-25-8
Molecular Formula	C15H22N2O2
Molecular Weight	262.35 g/mol
Synonyms	1-Carbobenzyloxy-3-(methylamino)piperidine; Benzyl 3-(Methylamino)piperidine-1-carboxylate; 3-(Methylamino)piperidine-1-carboxylic acid benzyl ester; 1-N-CBZ-3-(Methylamino)piperidine; N-Cbz-3-(Methylamino)piperidine; 3-Methylaminopiperidine-1-carboxylic Acid Benzyl Ester; 1-(Benzyloxycarbonyl)-3-(methylamino)piperidine
EINECS	Contact for details

Quality Control

Our 3-Methylamino-Piperidine-1-Carboxylic Acid Benzyl Ester is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure identity, purity, and consistency, meeting the high standards required for pharmaceutical R&D and advanced synthesis. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment and is available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Purity (HPLC, Area %)	≥ 98.5%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.