Description

Methyl 4-Bromo-1H-Pyrrolo[2,3-B]Pyridine-2-Carboxylate is a high-value brominated heterocyclic building block essential for advanced pharmaceutical and agrochemical research. This compound serves as a critical intermediate in the synthesis of complex molecules, particularly kinase inhibitors and other biologically active agents. It is primarily sought after by R&D chemists and process development scientists in the pharmaceutical, biotechnology, and fine chemical industries for constructing novel drug candidates.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of kinase inhibitors and other targeted therapeutic agents.
• Agrochemical Research: Building block for developing novel active ingredients with specific biological activity.
• Chemical Biology: Used in probe and tool compound development for studying biological pathways.
• Material Science: Potential monomer or precursor for specialty polymers and advanced organic materials.
• Contract Research & Manufacturing (CRO/CMO): Supplied to service organizations for custom synthesis and library production.
• Academic Research: Utilized in university and institutional labs for methodological development and novel compound discovery.

Basic Information

Product Name	Methyl 4-Bromo-1H-Pyrrolo[2,3-B]Pyridine-2-Carboxylate
CAS No.	1159982-21-4
Molecular Formula	C9H7BrN2O2
Molecular Weight	255.07 g/mol
Synonyms	4-Bromo-1H-pyrrolo[2,3-b]pyridine-2-carboxylic acid methyl ester; Methyl 4-bromo-1H-pyrrolo[2,3-b]pyridine-2-carboxylate; 1H-Pyrrolo[2,3-b]pyridine-2-carboxylic acid, 4-bromo-, methyl ester; 4-Bromo-1H-pyrrolo[2,3-b]pyridine-2-carboxylate methyl ester; 1159982-21-4
EINECS	Contact for details

Quality Control

Our Methyl 4-Bromo-1H-Pyrrolo[2,3-B]Pyridine-2-Carboxylate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. Certificates of Analysis (COA) documenting full specifications are provided with every shipment. We support compliance with cGMP, ICH Q7, and other relevant pharmaceutical guidelines for advanced intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms to reference standard
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.