Description

n-Methyl-3-[3-(5-Methoxycarbonylpyridyl)-5-Isoxazolecarboxylic Acid Methyl Ester is a high-purity, advanced pharmaceutical intermediate characterized by its complex heterocyclic structure. This compound is of significant value in medicinal chemistry for the synthesis of novel active pharmaceutical ingredients (APIs), particularly those targeting neurological and inflammatory pathways. It is primarily required by R&D laboratories and production facilities in the pharmaceutical and biotechnology sectors engaged in the development of new therapeutic agents.

Application

• Pharmaceutical Intermediate: A key building block in the multi-step synthesis of complex drug candidates, especially kinase inhibitors and other targeted therapies.
• Medicinal Chemistry Research: Used in lead optimization and structure-activity relationship (SAR) studies to develop new chemical entities with improved efficacy and safety profiles.
• Contract Research & Manufacturing (CRAM): Supplied to CDMOs for the scale-up and cGMP production of clinical trial materials and commercial APIs.
• Agrochemical Research: Potential application as a synthetic precursor for developing new crop protection agents with specific biological activity.
• Academic Research: Utilized in university and institutional labs for studying heterocyclic chemistry and developing novel synthetic methodologies.

Basic Information

Product Name	n-Methyl-3-[3-(5-Methoxycarbonylpyridyl)-5-Isoxazolecarboxylic Acid Methyl Ester
CAS No.	1159977-50-0
Molecular Formula	C14H12N2O5
Molecular Weight	288.26 g/mol
Synonyms	Methyl 3-(3-((5-(methoxycarbonyl)pyridin-3-yl))-1,2-oxazol-5-yl)propanoate; 5-Isoxazolecarboxylic acid, 3-[3-(5-methoxycarbonyl-3-pyridinyl)]-, methyl ester; Methyl 3-(3-(5-(methoxycarbonyl)pyridin-3-yl)isoxazol-5-yl)propanoate; 1159977-50-0; n-Methyl-3-[3-(5-Methoxycarbonyl-3-pyridyl)-5-Isoxazolecarboxylic Acid Methyl Ester
EINECS	Contact for details

Quality Control

Our n-Methyl-3-[3-(5-Methoxycarbonylpyridyl)-5-Isoxazolecarboxylic Acid Methyl Ester is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via NMR and mass spectrometry, to ensure it meets the stringent requirements for pharmaceutical R&D and production. Certificates of Analysis (COA) detailing all specifications and test results are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Keep the container tightly sealed in a dry environment to prevent moisture absorption.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Related Substances (HPLC)	Any individual impurity ≤ 0.5%
Total Impurities	≤ 2.0%
Residual Solvents (GC)	Complies with ICH Q3C guidelines
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.