Description

4-(4-Bromo-1-Butyn-1-Yl)-α,α-Dimethyl-Benzeneacetic Acid Methyl Ester is a specialized organic building block featuring a bromoalkyne functional group, making it a valuable intermediate for advanced synthetic chemistry. Its molecular architecture is designed for selective cross-coupling reactions, enabling the efficient construction of complex molecular frameworks. This compound is primarily utilized by research chemists and process development scientists in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of new drug candidates, particularly for constructing complex alkyne-linked bioactive molecules.
• Agrochemical Synthesis: Used in the production of advanced pesticides and herbicides where the bromoalkyne moiety allows for precise structural modifications.
• Material Science Research: Serves as a monomer or precursor in the development of novel polymers and functional materials with tailored properties.
• Chemical Biology Probes: Employed in the synthesis of molecular probes and tags for studying biological processes via click chemistry and other bioorthogonal reactions.
• Academic & Industrial R&D: A versatile reagent for methodological development in organic synthesis, including Sonogashira and other palladium-catalyzed cross-coupling reactions.

Basic Information

Product Name	4-(4-Bromo-1-Butyn-1-Yl)-α,α-Dimethyl-Benzeneacetic Acid Methyl Ester
CAS No.	1159977-16-8
Molecular Formula	C15H17BrO2
Molecular Weight	309.20 g/mol
Synonyms	Methyl 2-(4-(4-bromobut-1-yn-1-yl)phenyl)-2-methylpropanoate; Methyl 4-(4-bromo-1-butyn-1-yl)-alpha,α-dimethylbenzeneacetate; 2-(4-(4-Bromobut-1-yn-1-yl)phenyl)-2-methylpropanoic acid methyl ester; 4-(4-Bromobut-1-ynyl)-alpha,α-dimethylbenzeneacetic acid methyl ester; (4-(4-Bromobut-1-yn-1-yl)phenyl)(tert-butoxy)methanone precursor
EINECS	Contact for details

Quality Control

Our products undergo rigorous quality testing to ensure compliance with industry standards. Each batch is characterized using advanced analytical techniques to confirm identity, purity, and consistency. Certificates of Analysis (COA) detailing specific results for purity, impurities, and other critical parameters are available upon request. We adhere to strict quality management protocols to ensure supply reliability for your research and development projects.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from heat, sparks, and open flame. This material is light-sensitive (store away from light).

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Melting Point	Contact for details
Heavy Metals	< 20 ppm
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.