Description

Bis-(6-Bromo-Pyridin-3-Yl)-Methanone is a high-purity, specialized organic building block featuring a central ketone bridge between two brominated pyridine rings. This compound is critical for facilitating complex molecular assembly in advanced research and development, offering a versatile and reactive scaffold for constructing sophisticated heterocyclic architectures. It is primarily sought by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and material science industries for applications in medicinal chemistry, ligand synthesis, and the creation of functional polymers.

Application

• Pharmaceutical Intermediate: Serves as a key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for kinase inhibitors and other targeted therapies.
• Agrochemical Synthesis: Used in the research and development of novel herbicides, fungicides, and insecticides, leveraging its halogenated pyridine structure.
• Ligand and Catalyst Development: Acts as a foundational unit for constructing chelating ligands used in homogeneous catalysis and metal-organic frameworks (MOFs).
• Material Science Research: Employed in the development of organic electronic materials, such as semiconductors and light-emitting components, due to its conjugated system.
• Chemical Biology Probes: Utilized as a building block for creating molecular probes and tags to study biological processes and protein interactions.
• Custom Synthesis and Contract Manufacturing: A vital starting material for custom synthesis projects requiring specific, complex heterocyclic structures.

Basic Information

Product Name	Bis-(6-Bromo-Pyridin-3-Yl)-Methanone
CAS No.	1159976-89-2
Molecular Formula	C11H6Br2N2O
Molecular Weight	341.98 g/mol
Synonyms	Di(6-bromopyridin-3-yl)methanone; 3,3'-Dibromo-5,5'-dicarbonyl-dipyridine; Methanone, bis(6-bromo-3-pyridinyl)-; 1,1'-(6-Bromopyridin-3-yl)methanone; (6-Bromo-3-pyridinyl)(6-bromo-3-pyridinyl)methanone; Bis(6-bromo-3-pyridyl) ketone; 3-Pyridinemethanone, 6-bromo-, homopolymer
EINECS	Contact for details

Quality Control

Our Bis-(6-Bromo-Pyridin-3-Yl)-Methanone is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical specifications. Our quality commitment supports compliance with cGMP and ICH guidelines for advanced intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, handling and packaging should minimize exposure to direct light.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.