Description

(R)-Pinocembrin 7-Benzyl Ester is a high-purity, semi-synthetic derivative of the natural flavonoid pinocembrin, characterized by its specific (R)-enantiomeric configuration and a benzyl group at the 7-position. This structural modification enhances its lipophilicity and stability, making it a critical chiral intermediate and reference standard for advanced research and development. It is primarily sought by pharmaceutical, nutraceutical, and fine chemical industries for applications in chiral synthesis, metabolic studies, and the development of bioactive flavonoid-based compounds.

Application

• Pharmaceutical Intermediate: Serves as a key chiral building block in the synthesis of novel therapeutic agents targeting inflammation and oxidative stress.
• Reference Standard: Used as a high-purity analytical standard for quality control and method validation in HPLC and LC-MS assays.
• Biochemical Research: Employed in enzymatic and metabolic pathway studies to investigate the activity and fate of flavonoid derivatives.
• Nutraceutical Development: Acts as a precursor or model compound for developing enhanced bioavailability forms of flavonoid supplements.
• Asymmetric Synthesis: Utilized in chiral catalysis and synthesis research due to its defined stereochemistry.
• Cosmeceutical Actives: Investigated for potential use in advanced skincare formulations for its antioxidant properties.

Basic Information

Product Name	(R)-Pinocembrin 7-Benzyl Ester
CAS No.	1159852-74-0
Molecular Formula	C23H20O5
Molecular Weight	376.40 g/mol
Synonyms	(R)-5,7-Dihydroxyflavanone 7-benzyl ether; (2R)-5,7-Dihydroxy-2-phenyl-2,3-dihydro-4H-chromen-4-one 7-benzyl ether; (R)-Pinocembrin 7-O-benzyl ether; 7-Benzyloxy-5-hydroxy-(2R)-flavanone; Benzyl (R)-pinocembrin-7-yl ether; (2R)-5-Hydroxy-7-(phenylmethoxy)-2-phenyl-4-chromanone
EINECS	Contact for details

Quality Control

Our (R)-Pinocembrin 7-Benzyl Ester is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral HPLC for enantiomeric purity, NMR for structural confirmation, and standard pharmacopeial tests to ensure identity, potency, and purity. Certificates of Analysis (COA) detailing all specifications are provided and can be tailored to meet specific client or regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). The compound may be light-sensitive; prolonged exposure to light should be avoided.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Enantiomeric Purity (Chiral HPLC)	≥ 99.0% (R)-isomer
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.