Description

8-Fluoro-[1,2,4]Triazolo[4,3-A]Pyridine-3-Carboxylic Acid is a high-value heterocyclic building block and advanced pharmaceutical intermediate. This compound is critical for medicinal chemistry research and development, particularly in the synthesis of novel active pharmaceutical ingredients (APIs) targeting central nervous system and metabolic disorders. It is primarily utilized by pharmaceutical R&D laboratories, agrochemical innovators, and fine chemical manufacturers seeking to incorporate its unique fused triazolopyridine scaffold into new molecular entities.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, especially for neurological and psychiatric applications.
• Medicinal Chemistry Research: Serves as a versatile scaffold for structure-activity relationship (SAR) studies and library synthesis in drug discovery.
• Agrochemical Development: Used in the research and synthesis of new-generation pesticides and herbicides.
• Ligand Synthesis: Employed in the creation of specialized ligands for catalysis and material science applications.
• Chemical Biology Probes: Acts as a core structure for developing molecular probes to study biological pathways.
• Fine Chemical Synthesis: A building block for synthesizing complex, high-value specialty chemicals.

Basic Information

Product Name	8-Fluoro-[1,2,4]Triazolo[4,3-A]Pyridine-3-Carboxylic Acid
CAS No.	1159831-26-1
Molecular Formula	C7H4FN3O2
Molecular Weight	181.12 g/mol
Synonyms	8-Fluoro[1,2,4]triazolo[4,3-a]pyridine-3-carboxylic acid; 8-Fluoro-1,2,4-triazolo[4,3-a]pyridine-3-carboxylic acid; 1159831-26-1; 8-Fluoro-[1,2,4]triazolo[4,3-a]pyridine-3-carboxylic acid; 8-Fluoro-1H-[1,2,4]triazolo[4,3-a]pyridine-3-carboxylic acid; 8-Fluoro-1,2,4-triazolo[4,3-a]pyridin-3-carboxylic acid
EINECS	Contact for details

Quality Control

Our 8-Fluoro-[1,2,4]Triazolo[4,3-A]Pyridine-3-Carboxylic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and residual solvent analysis. We provide comprehensive Certificates of Analysis (COA) with each shipment to ensure traceability and compliance with your research or production standards.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its chemical nature as a strong acid/organic solvent, it should be kept away from incompatible materials such as strong bases and oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.