Description

7-Bromo-2-Methylimidazo[1,2-A]-Pyridine-3-Carboxylic Acid is a high-purity, advanced pharmaceutical intermediate with the CAS registry number 1159831-07-8. This heterocyclic carboxylic acid derivative is a critical building block in modern medicinal chemistry, valued for its precise molecular architecture that enables the synthesis of complex bioactive molecules. It is primarily sought after by research institutions and pharmaceutical manufacturers engaged in the development of novel therapeutic agents, particularly within oncology and central nervous system (CNS) drug discovery pipelines.

Application

• Pharmaceutical Intermediate: Serves as a key synthetic precursor in the research and production of active pharmaceutical ingredients (APIs) with imidazopyridine cores.
• Medicinal Chemistry Research: Utilized as a versatile scaffold for structure-activity relationship (SAR) studies and the design of new drug candidates.
• Organic Synthesis Building Block: Employed in cross-coupling reactions, such as Suzuki or Buchwald-Hartwig amination, to introduce complex functionalities.
• Chemical Reference Standard: Used as a high-purity analytical standard for quality control and method development in regulatory and R&D laboratories.
• Biochemical Probe Development: Acts as a starting material for creating tool compounds to study biological pathways and target validation.

Basic Information

Product Name	7-Bromo-2-Methylimidazo[1,2-A]-Pyridine-3-Carboxylic Acid
CAS No.	1159831-07-8
Molecular Formula	C9H7BrN2O2
Molecular Weight	255.07 g/mol
Synonyms	7-Bromo-2-methylimidazo[1,2-a]pyridine-3-carboxylic acid; 2-Methyl-7-bromoimidazo[1,2-a]pyridine-3-carboxylic acid; Imidazo[1,2-a]pyridine-3-carboxylic acid, 7-bromo-2-methyl-; 1159831-07-8; 7-Bromo-2-methyl-3-imidazo[1,2-a]pyridinecarboxylic acid; 3-Carboxy-7-bromo-2-methylimidazo[1,2-a]pyridine
EINECS	Contact for details

Quality Control

Our 7-Bromo-2-Methylimidazo[1,2-A]-Pyridine-3-Carboxylic Acid is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with every shipment, documenting all critical quality attributes. Our production adheres to cGMP principles where applicable, supporting its use in regulated research and development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and must be kept under inert atmosphere or in a desiccator to prevent degradation. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥98.0%
Water Content (KF)	≤0.5%
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.