Description

2,8-Diazaspiro[4.5]Decane Hydrochloride is a high-purity, heterocyclic organic compound featuring a unique spirocyclic structure. This versatile building block is critical for pharmaceutical research and development, particularly in the synthesis of novel active pharmaceutical ingredients (APIs). It serves as a key intermediate for medicinal chemists and process development scientists in the pharmaceutical, agrochemical, and fine chemical industries seeking to develop new therapeutic agents.

Application

• Pharmaceutical Intermediate: A crucial building block for the synthesis of complex drug candidates, particularly those targeting central nervous system (CNS) disorders.
• Medicinal Chemistry Research: Used in hit-to-lead and lead optimization campaigns to explore structure-activity relationships (SAR) due to its constrained, three-dimensional spirocyclic scaffold.
• API Synthesis: Serves as a core structural element in the multi-step synthesis of potential Active Pharmaceutical Ingredients (APIs).
• Chemical Biology Probes: Can be utilized to create specialized molecular probes for studying biological pathways and target engagement.
• Agrochemical Development: Acts as an intermediate in the research and synthesis of new crop protection agents and pesticides.
• Ligand Synthesis for Catalysis: Potential use in constructing sophisticated ligand systems for asymmetric catalysis and metal-organic frameworks (MOFs).

Basic Information

Product Name	2,8-Diazaspiro[4.5]Decane Hydrochloride
CAS No.	1159826-64-8
Molecular Formula	C8H17ClN2
Molecular Weight	176.69 g/mol
Synonyms	2,8-Diazaspiro[4.5]decane, hydrochloride; 2,8-Diazaspiro[4.5]decane HCl; 1,4-Diazaspiro[4.5]decane hydrochloride (isomer); Spiro[4.5]decane-2,8-diamine hydrochloride; 2,8-Diazaspiro[4.5]decan hydrochloride; 8-Aza-2-azoniaspiro[4.5]decane chloride
EINECS	Contact for details

Quality Control

Our 2,8-Diazaspiro[4.5]Decane Hydrochloride is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and KF titration for moisture content, to ensure it meets the high standards required for research and development. A Certificate of Analysis (COA) detailing all specifications is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to prevent moisture absorption, which can affect product stability and performance.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.