Description

5,8-Diaza-Spiro[3.5]Nonane Dihydrochloride is a high-purity, advanced pharmaceutical intermediate featuring a unique spirocyclic diaza structure. This compound is valued for its role as a critical building block in the synthesis of novel active pharmaceutical ingredients (APIs), particularly in the development of central nervous system (CNS) and oncology therapeutics. It is primarily sought after by research institutions, custom synthesis organizations, and pharmaceutical companies engaged in drug discovery and process development.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of complex drug candidates, especially those targeting neurological disorders and cancer.
• Organic Synthesis Building Block: Utilized in medicinal chemistry for constructing spirocyclic and bridged heterocyclic scaffolds with potential biological activity.
• Ligand and Catalyst Development: Serves as a starting material for creating novel chelating ligands or organocatalysts due to its nitrogen-rich architecture.
• Academic and R&D: Used in research laboratories for studying structure-activity relationships (SAR) and developing new synthetic methodologies.
• Custom Synthesis and Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for scale-up and GMP production of client-specific molecules.

Basic Information

Product Name	5,8-Diaza-Spiro[3.5]Nonane Dihydrochloride
CAS No.	1159824-37-9
Molecular Formula	C7H14N2·2HCl
Molecular Weight	207.11 g/mol
Synonyms	5,8-Diazaspiro[3.5]nonane dihydrochloride; 5,8-Diaza-spiro[3.5]nonane hydrochloride; 1,4-Diazaspiro[4.4]nonane dihydrochloride (common misnomer); Spiro[3.5]nonane-5,8-diamine dihydrochloride; 5,8-Diaza-spiro[3.5]nonane, 2HCl; 1159824-37-9; 5,8-Diaza-spiro[3.5]nonane HCl salt
EINECS	Contact for details

Quality Control

Our 5,8-Diaza-Spiro[3.5]Nonane Dihydrochloride is produced under strict quality management systems. Each batch undergoes comprehensive analytical testing to ensure identity, purity, and consistency. We provide full traceability and Certificates of Analysis (COA) are available for every shipment, detailing key parameters such as assay, impurity profile, and residual solvents. Our quality commitment supports applications in research and pre-clinical development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under anhydrous conditions. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.