Description

tert-Butyl 4-(1-Amino-3-Ethoxy-3-Oxopropyl)Piperidine-1-Carboxylate Hydrochloride is a high-purity, protected amino acid derivative and a key pharmaceutical intermediate. Its primary value lies in its role as a versatile building block for the synthesis of complex molecules, particularly in medicinal chemistry and drug discovery. This compound is essential for research and development chemists in the pharmaceutical and biotechnology industries, where it is used to construct novel active pharmaceutical ingredients (APIs) and peptide mimetics.

Application

• Pharmaceutical Intermediate: A critical building block in the synthesis of novel drug candidates, particularly for central nervous system (CNS) and metabolic disorder targets.
• Peptidomimetic Synthesis: Used to create non-peptide compounds that mimic the structure and function of peptides, enhancing metabolic stability and bioavailability.
• Medicinal Chemistry Research: Serves as a versatile scaffold for structure-activity relationship (SAR) studies and lead optimization in drug discovery programs.
• API Development: Incorporated into the synthetic pathways for developing new Active Pharmaceutical Ingredients (APIs), leveraging its protected amine and ester functionalities.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for the production of specialized compounds and reference standards.

Basic Information

Product Name	tert-Butyl 4-(1-Amino-3-Ethoxy-3-Oxopropyl)Piperidine-1-Carboxylate Hydrochloride
CAS No.	1159824-10-8
Molecular Formula	C15H28N2O4 • HCl
Molecular Weight	336.86 g/mol (Free base: 300.40 g/mol)
Synonyms	1-Boc-4-(1-Amino-3-ethoxy-3-oxopropyl)piperidine hydrochloride; 1-(tert-Butoxycarbonyl)-4-(1-amino-3-ethoxy-3-oxopropyl)piperidine hydrochloride; 4-(1-Amino-3-ethoxy-3-oxopropyl)-1-piperidinecarboxylic acid 1,1-dimethylethyl ester hydrochloride; tert-Butyl 4-(1-amino-3-ethoxy-3-oxopropyl)-1-piperidinecarboxylate hydrochloride; 3-Amino-3-(1-Boc-4-piperidyl)propionic acid ethyl ester hydrochloride; 1159824-10-8; Boc-Pip(AEE)-OH•HCl
EINECS	Contact for details

Quality Control

Our tert-Butyl 4-(1-Amino-3-Ethoxy-3-Oxopropyl)Piperidine-1-Carboxylate Hydrochloride is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity suitable for research and pharmaceutical applications. All materials are accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We adhere to cGMP principles where applicable to support our clients' regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and must be kept under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep the container tightly sealed when not in use.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms
Identification (IR)	Conforms to reference spectrum
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.