Description

1-(2-Chloropyridine-3-Carbonyl)-4-Piperidinone is a high-value, heterocyclic organic building block of significant interest in advanced chemical synthesis. This compound matters as a key intermediate for constructing complex molecular architectures, particularly in the development of novel active pharmaceutical ingredients (APIs). It is primarily needed by research institutions and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries for drug discovery and process chemistry applications.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of potential drug candidates, particularly those targeting the central nervous system (CNS) and other therapeutic areas.
• Agrochemical Research: Used in the development of new pesticides and herbicides, leveraging its piperidinone and chloropyridine motifs.
• Chemical Biology Probe Synthesis: Serves as a scaffold for creating tool compounds and probes to study biological pathways and protein function.
• Ligand and Catalyst Development: Employed in the preparation of novel ligands for metal-catalyzed reactions or as a component in organocatalysts.
• Custom Synthesis and Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for custom synthesis projects requiring specific chiral or structural complexity.
• Academic and R&D Laboratories: Utilized in fundamental organic chemistry research for methodology development and the exploration of new heterocyclic reactions.

Basic Information

Product Name	1-(2-Chloropyridine-3-Carbonyl)-4-Piperidinone
CAS No.	1159822-97-5
Molecular Formula	C11H9ClN2O2
Molecular Weight	236.66 g/mol
Synonyms	4-Piperidinone, 1-[(2-chloro-3-pyridinyl)carbonyl]-; 1-(2-Chloro-3-pyridinecarbonyl)-4-piperidinone; 1-(2-Chloronicotinoyl)-4-piperidinone; 1-(2-Chloropyridine-3-carbonyl)piperidin-4-one; 2-Chloro-N-(4-oxopiperidin-1-yl)nicotinamide; 1159822-97-5
EINECS	Contact for details

Quality Control

Our 1-(2-Chloropyridine-3-Carbonyl)-4-Piperidinone is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment to guarantee compliance with your research or production requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a dry environment to prevent degradation. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.