Description

6-Cyclopropylpyridin-3-Amine CAS NO 1159821-66-5 is a high-purity, functionalized pyridine derivative featuring a cyclopropyl substituent, serving as a critical building block in advanced organic synthesis. This compound is valued for its unique structural motif that imparts specific steric and electronic properties to target molecules, enabling the development of novel compounds with enhanced biological or material characteristics. It is primarily sought after by research and development chemists in the pharmaceutical and agrochemical industries for the synthesis of active ingredients and novel chemical entities.

Application

• Pharmaceutical Intermediate: A key synthon for the research and development of new drug candidates, particularly in kinase inhibitor and central nervous system (CNS) active compound libraries.
• Agrochemical Synthesis: Used in the creation of novel pesticides and herbicides, where the cyclopropyl group can contribute to metabolic stability and binding affinity.
• Material Science Research: Serves as a precursor for ligands in catalytic systems or for the synthesis of functional organic materials and polymers.
• Chemical Biology Probes: Employed in the design and synthesis of molecular probes for studying biological pathways and protein interactions.
• Custom Synthesis & Contract Manufacturing: A vital starting material for custom synthesis projects and scale-up processes under cGMP or ISO standards.

Basic Information

Product Name	6-Cyclopropylpyridin-3-Amine
CAS No.	1159821-66-5
Molecular Formula	C8H10N2
Molecular Weight	134.18 g/mol
Synonyms	3-Amino-6-cyclopropylpyridine; 6-Cyclopropyl-3-pyridinamine; 6-Cyclopropylpyridin-3-ylamine; 3-Pyridinamine, 6-cyclopropyl-; 6-Cyclopropyl-3-aminopyridine; 5-Amino-2-cyclopropylpyridine
EINECS	Contact for details

Quality Control

Our 6-Cyclopropylpyridin-3-Amine is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles, verified by techniques including HPLC, GC, and NMR. We support cGMP and ISO 9001 compliant production for pharmaceutical applications, ensuring traceability and regulatory support.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.