Description

2-(3-Pyridinyl)-1,3-Thiazol-5-Amine Hydrochloride is a high-purity organic building block and pharmaceutical intermediate of significant commercial interest. This heterocyclic compound, featuring fused pyridine and thiazole rings, is valued for its role in the synthesis of complex molecules targeting various biological pathways. It is primarily sought by research institutions and manufacturers in the pharmaceutical and agrochemical sectors for drug discovery and development programs.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel active pharmaceutical ingredients (APIs), particularly for kinase inhibitors and other targeted therapies.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and insecticides, leveraging its heterocyclic scaffold for bioactivity.
• Chemical Biology & Proteomics: Serves as a valuable scaffold or linker in the design of chemical probes for studying enzyme function and protein interactions.
• Material Science Research: Investigated as a building block for organic electronic materials, such as ligands in coordination polymers or components in organic semiconductors.
• Academic & Contract Research: Utilized in university and CRO laboratories for methodological development and exploratory synthesis in medicinal chemistry.

Basic Information

Product Name	2-(3-Pyridinyl)-1,3-Thiazol-5-Amine Hydrochloride
CAS No.	1159821-51-8
Molecular Formula	C8H8N3S • HCl
Molecular Weight	215.69 g/mol (Free base: 179.23 g/mol)
Synonyms	5-Amino-2-(pyridin-3-yl)-1,3-thiazole Hydrochloride; 2-(3-Pyridyl)-1,3-thiazol-5-amine HCl; 3-(5-Amino-1,3-thiazol-2-yl)pyridine hydrochloride; 2-Pyridin-3-yl-1,3-thiazol-5-amine hydrochloride; 1159821-51-8; 2-(3-Pyridinyl)-5-thiazolamine hydrochloride
EINECS	Contact for details

Quality Control

Our 2-(3-Pyridinyl)-1,3-Thiazol-5-Amine Hydrochloride is manufactured under strict quality management systems. Each batch is subjected to rigorous analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and residual solvent analysis. We provide comprehensive Certificates of Analysis (COA) with each shipment to ensure traceability and compliance with your research or cGMP starting material requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed in a dry environment to prevent moisture absorption.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.