Description

5-Cyclobutylpyridin-2(1H)-One is a high-purity, advanced pharmaceutical intermediate with the CAS registry number 1159818-55-9. This heterocyclic compound is valued for its role as a critical building block in the synthesis of novel active pharmaceutical ingredients (APIs), particularly in medicinal chemistry research and development. It is primarily sought after by pharmaceutical R&D laboratories, contract research organizations (CROs), and fine chemical manufacturers engaged in developing new therapeutic agents.

Application

• Pharmaceutical Intermediate: Serves as a key precursor in the synthesis of complex drug candidates targeting various disease pathways.
• Medicinal Chemistry Research: Used extensively in hit-to-lead and lead optimization stages for constructing novel pyridone-based molecular scaffolds.
• API Development: Integral in the development and scale-up processes for new Active Pharmaceutical Ingredients (APIs).
• Chemical Biology Probes: Employed in the design and synthesis of chemical probes for studying biological targets and mechanisms of action.
• Agrochemical Research: Potential use as an intermediate in the development of new agrochemicals and plant protection agents.
• Material Science: Can be utilized in the synthesis of specialized organic materials and ligands for catalysis.

Basic Information

Product Name	5-Cyclobutylpyridin-2(1H)-One
CAS No.	1159818-55-9
Molecular Formula	C9H11NO
Molecular Weight	149.19 g/mol
Synonyms	5-Cyclobutyl-2-hydroxypyridine; 5-Cyclobutyl-2-pyridone; 2(1H)-Pyridinone, 5-cyclobutyl-; 5-Cyclobutyl-1H-pyridin-2-one; 5-Cyclobutylpyridin-2-ol; 5-Cyclobutyl-2-pyridinol; 1159818-55-9
EINECS	Contact for details

Quality Control

Our 5-Cyclobutylpyridin-2(1H)-One is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity suitable for research and development applications. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We adhere to relevant industry standards and can support development projects requiring material for pre-clinical and clinical studies.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (typically 15-25°C). Keep away from incompatible materials. For long-term storage, consider storing under an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.