Description

2-Bromo-5-(Pyrrolidin-3-Yl)Pyridine is a high-value brominated pyridine derivative featuring a pyrrolidine substituent, serving as a critical building block in modern synthetic chemistry. This compound is essential for medicinal chemistry research and pharmaceutical development, enabling the construction of complex molecular architectures. It is primarily utilized by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and advanced materials sectors.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for central nervous system (CNS) and oncology targets.
• Medicinal Chemistry Scaffold: Used in hit-to-lead and lead optimization campaigns to explore structure-activity relationships (SAR) due to its versatile bromine handle and nitrogen-rich heterocyclic core.
• Agrochemical Research: Serves as a building block for developing novel crop protection agents and pesticides.
• Ligand Synthesis: Employed in the preparation of nitrogen-donor ligands for catalysis and coordination chemistry.
• Chemical Biology Probes: Utilized to create tool compounds and molecular probes for studying biological pathways.
• Material Science: A potential monomer or functionalizing agent for advanced polymers and electronic materials.

Basic Information

Item	Detail
Product Name	2-Bromo-5-(Pyrrolidin-3-Yl)Pyridine
CAS No.	1159817-25-0
Molecular Formula	C9H11BrN2
Molecular Weight	227.10 g/mol
Synonyms	5-(Pyrrolidin-3-yl)-2-bromopyridine; 2-Bromo-5-(3-pyrrolidinyl)pyridine; 2-Bromo-5-pyrrolidin-3-ylpyridine; 1159817-25-0; 2-Bromo-5-(pyrrolidin-3-yl)pyridine; Pyridine, 2-bromo-5-(3-pyrrolidinyl)-; 2-Br-5-Pyrrolidin-3-yl-Pyridine
EINECS	Contact for details

Quality Control

Our 2-Bromo-5-(Pyrrolidin-3-Yl)Pyridine is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide full traceability and detailed Certificates of Analysis (COA) with every shipment, confirming compliance with your specified requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to exclude moisture. For long-term storage, consider using desiccants or an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC/MS)	Conforms
Purity (HPLC)	≥97.0%
Water Content (KF)	≤0.5%
Residue on Ignition	≤0.1%
Single Unknown Impurity (HPLC)	≤1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.