Description

4-Cyclobutylpyridin-2(1H)-One is a high-purity heterocyclic building block of significant interest in advanced organic synthesis. This compound matters as a key intermediate for constructing complex molecular architectures, particularly in the development of novel active pharmaceutical ingredients (APIs). It is primarily needed by research chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for creating new compounds with targeted biological activities.

Application

• Pharmaceutical Intermediate: Serves as a critical precursor in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders and other therapeutic areas.
• Agrochemical Research: Used in the development of new active ingredients for crop protection products, leveraging its unique pyridone-cyclobutyl structure.
• Ligand & Catalyst Development: Acts as a versatile scaffold for creating novel ligands in asymmetric catalysis and metal-organic frameworks (MOFs).
• Material Science: Employed in the research and synthesis of advanced organic electronic materials and functional polymers.
• Chemical Biology Probes: Utilized as a building block for creating molecular probes to study biological pathways and enzyme functions.
• Custom Synthesis & Contract Manufacturing: A key starting material for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) serving global clients.

Basic Information

Product Name	4-Cyclobutylpyridin-2(1H)-One
CAS No.	1159816-14-4
Molecular Formula	C9H11NO
Molecular Weight	149.19 g/mol
Synonyms	4-Cyclobutyl-2-hydroxypyridine; 4-Cyclobutyl-2(1H)-pyridinone; 2(1H)-Pyridinone, 4-cyclobutyl-; 4-Cyclobutyl-1H-pyridin-2-one; 4-Cyclobutylpyridin-2-ol; 4-Cyclobutyl-2-pyridone; 2-Hydroxy-4-cyclobutylpyridine
EINECS	Contact for details

Quality Control

Our 4-Cyclobutylpyridin-2(1H)-One is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical quality attributes. Our production adheres to cGMP principles where applicable, ensuring reliability for research and scale-up activities.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Keep away from incompatible materials such as strong oxidizing agents. For long-term storage, consider an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white powder or crystalline solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.