Description

5-Hydroxy-2-(Thiophen-2-Yl)Pyridine is a high-value heterocyclic building block that combines pyridine and thiophene pharmacophores, making it a critical intermediate for advanced chemical synthesis. Its unique structure offers versatile reactivity for constructing complex molecules with tailored electronic and binding properties. This compound is primarily sought after by research institutions and pharmaceutical companies engaged in the development of novel active pharmaceutical ingredients (APIs), agrochemicals, and organic electronic materials.

Application

• Pharmaceutical Intermediate: Key synthon for the research and development of new drug candidates, particularly in kinase inhibitor and central nervous system (CNS) therapeutic areas.
• Agrochemical Synthesis: Used in the creation of advanced herbicides and fungicides that leverage its heterocyclic scaffold for enhanced biological activity.
• Material Science Research: Serves as a precursor for organic semiconductors, ligands for metal-organic frameworks (MOFs), and other functional materials due to its electron-rich character.
• Chemical Research & Development: A versatile building block in medicinal and synthetic chemistry for constructing complex polyheterocyclic systems.
• Ligand Synthesis: Used to prepare novel chelating ligands for catalysis and coordination chemistry applications.

Basic Information

Product Name	5-Hydroxy-2-(Thiophen-2-Yl)Pyridine
CAS No.	1159815-70-9
Molecular Formula	C9H7NOS
Molecular Weight	177.22 g/mol
Synonyms	2-(Thiophen-2-yl)pyridin-5-ol; 5-Hydroxy-2-(2-thienyl)pyridine; 2-(2-Thienyl)-5-hydroxypyridine; 5-Hydroxy-2-thiophen-2-ylpyridine; 5-Pyridinol, 2-(2-thienyl)-; 1159815-70-9
EINECS	Contact for details

Quality Control

Our 5-Hydroxy-2-(Thiophen-2-Yl)Pyridine is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with every shipment, confirming compliance with agreed specifications. Custom synthesis and purity grades (including research and GMP grades) are available to meet specific project requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). The compound may be light-sensitive; prolonged exposure to light should be avoided.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (HPLC)	Conforms
Identification (IR)	Conforms
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.