Description

4-(3-Fluorophenyl)Pyridin-2-Amine is a high-purity fluorinated pyridine derivative, serving as a critical building block in advanced organic synthesis. Its molecular structure, featuring both an amine and a fluorinated aromatic ring, makes it a versatile intermediate for constructing complex molecules with tailored properties. This compound is essential for research and development in the pharmaceutical and agrochemical industries, where it is used to create novel active ingredients.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for candidates targeting central nervous system (CNS) disorders and oncology.
• Agrochemical Research: Used in developing new generations of herbicides and fungicides, where the fluorine atom enhances biological activity and metabolic stability.
• Material Science: Serves as a monomer or functionalization agent for creating specialty polymers and liquid crystals with specific electronic or optical properties.
• Chemical Synthesis: A valuable reagent for Suzuki-Miyaura and other cross-coupling reactions to build biaryl systems common in medicinal chemistry.
• Life Science Research: Utilized as a biochemical tool and standard in analytical method development and proteomics research.

Basic Information

Product Name	4-(3-Fluorophenyl)Pyridin-2-Amine
CAS No.	1159815-31-2
Molecular Formula	C11H9FN2
Molecular Weight	188.20 g/mol
Synonyms	2-Amino-4-(3-fluorophenyl)pyridine; 4-(3-Fluorophenyl)-2-pyridinamine; 3-Fluoro-4-(2-aminopyridin-4-yl)benzene; 4-(m-Fluorophenyl)pyridin-2-amine; 2-Pyridinamine, 4-(3-fluorophenyl)-; 1159815-31-2
EINECS	Contact for details

Quality Control

Every batch of 4-(3-Fluorophenyl)Pyridin-2-Amine is manufactured under a strict quality management system and undergoes comprehensive analytical testing to ensure identity, purity, and consistency. Our standard pharmaceutical intermediate grade meets stringent internal specifications, supported by a detailed Certificate of Analysis (COA) for each lot. We support cGMP compliance for advanced applications, and specifications can be customized to meet specific project requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). Due to its sensitivity to oxidation, long-term storage under an inert atmosphere (e.g., nitrogen or argon) is recommended for optimal stability. Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.