Description

6-Cyclobutylpyridin-3-Amine CAS NO 1159815-22-1 is a high-purity, functionalized pyridine derivative that serves as a critical building block in advanced organic synthesis. Its unique cyclobutyl-substituted amine structure makes it a valuable intermediate for constructing complex molecular architectures with specific steric and electronic properties. This compound is primarily sought after by research and development teams in the pharmaceutical and agrochemical industries for the discovery and development of new active ingredients.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of novel small-molecule drug candidates, particularly in kinase inhibitor and central nervous system (CNS) therapeutic areas.
• Agrochemical Synthesis: Used in the creation of advanced herbicides, fungicides, and insecticides, where the pyridine-amine core contributes to biological activity.
• Ligand and Catalyst Development: Serves as a precursor for chelating ligands in transition metal catalysis and organocatalysis.
• Material Science Research: Employed in the synthesis of functional organic materials, such as dyes, photoactive compounds, and conductive polymers.
• Chemical Biology Probes: Utilized as a scaffold for developing molecular probes to study biological pathways and protein functions.
• Custom Synthesis and Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for custom synthesis projects requiring this specific bicyclic amine.

Basic Information

Product Name	6-Cyclobutylpyridin-3-Amine
CAS No.	1159815-22-1
Molecular Formula	C9H12N2
Molecular Weight	148.21 g/mol
Synonyms	3-Amino-6-cyclobutylpyridine; 6-Cyclobutyl-3-pyridinamine; 6-Cyclobutylpyridin-3-ylamine; 3-Pyridinamine, 6-cyclobutyl-; 6-Cyclobutyl-3-aminopyridine; 5-Amino-2-cyclobutylpyridine; 2-Cyclobutyl-5-aminopyridine
EINECS	Contact for details

Quality Control

Every batch of 6-Cyclobutylpyridin-3-Amine is manufactured under strict quality management systems. Our products undergo rigorous analytical testing, including HPLC, GC, and NMR, to ensure high chemical purity and identity confirmation. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with each shipment to guarantee supply consistency and traceability for your critical R&D and scale-up processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.