Description

5-Bromo-2-Cyclobutylpyridine is a high-purity, versatile brominated pyridine derivative that serves as a critical building block in advanced organic synthesis. Its unique structure, combining a halogenated pyridine core with a cyclobutyl substituent, makes it an invaluable intermediate for constructing complex molecular architectures. This compound is primarily sought after by research and development teams in the pharmaceutical and agrochemical industries for applications in medicinal chemistry and material science.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for candidates targeting central nervous system (CNS) disorders and oncology.
• Agrochemical Synthesis: Used in the development of novel herbicides, fungicides, and insecticides, leveraging the pyridine moiety's bioactivity.
• Ligand & Catalyst Development: Serves as a starting material for creating specialized ligands in transition metal catalysis and organometallic chemistry.
• Material Science Research: Employed in the design and synthesis of organic electronic materials, such as charge-transport layers and light-emitting components.
• Chemical Biology Probes: Utilized to create tagged molecules or inhibitors for studying enzyme function and biological pathways.
• Custom Synthesis & Contract Manufacturing: A fundamental substrate for custom synthesis services catering to R&D and pilot-scale production needs.

Basic Information

Product Name	5-Bromo-2-Cyclobutylpyridine
CAS No.	1159815-16-3
Molecular Formula	C9H10BrN
Molecular Weight	212.09 g/mol
Synonyms	2-Cyclobutyl-5-bromopyridine; 5-Bromo-2-cyclobutylpyridine; Pyridine, 5-bromo-2-cyclobutyl-; 1159815-16-3; 5-Bromo-2-cyclobutyl-pyridine; 2-(5-Bromopyridin-2-yl)cyclobutane (tautomeric form)
EINECS	Contact for details

Quality Control

Every batch of 5-Bromo-2-Cyclobutylpyridine is manufactured under strict quality management systems. We employ advanced analytical techniques, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. Our products undergo rigorous quality testing to ensure compliance with industry standards. Certificates of Analysis (COA) with detailed chromatographic data are available upon request to support your quality assurance and regulatory documentation.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from heat, sparks, and open flame. For long-term storage, consider storing under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Related Substances (HPLC)	Total impurities ≤ 3.0%
Residual Solvents (GC)	Complies with ICH guidelines
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.