Description

5-(Tetrahydro-2H-Pyran-4-Yl)Pyridin-2-Amine is a high-purity, advanced pharmaceutical intermediate featuring a unique pyridine-pyran hybrid scaffold. This compound is valued for its role as a critical building block in the synthesis of novel active pharmaceutical ingredients (APIs), particularly in central nervous system (CNS) and oncology research. It is essential for medicinal chemists and process development scientists in pharmaceutical R&D and fine chemical manufacturing seeking to develop new therapeutic candidates.

Application

• Pharmaceutical Intermediate: A key synthon for the development of novel drug candidates, especially in neurological and oncological therapeutic areas.
• Organic Synthesis Building Block: Used in cross-coupling reactions, amide formations, and other transformations to construct complex molecular architectures.
• Medicinal Chemistry Research: Serves as a core scaffold for structure-activity relationship (SAR) studies and library synthesis in drug discovery programs.
• Process Chemistry & Scale-Up: Employed in the development and optimization of scalable synthetic routes for potential API manufacturing.
• Ligand & Catalyst Precursor: Can be utilized in the synthesis of specialized ligands for catalysis or metal-organic frameworks.

Basic Information

Product Name	5-(Tetrahydro-2H-Pyran-4-Yl)Pyridin-2-Amine
CAS No.	1159814-73-9
Molecular Formula	C10H14N2O
Molecular Weight	178.23 g/mol
Synonyms	2-Amino-5-(tetrahydro-2H-pyran-4-yl)pyridine; 5-(Oxan-4-yl)pyridin-2-amine; 5-(Tetrahydropyran-4-yl)pyridin-2-amine; 2-Pyridinamine, 5-(tetrahydro-2H-pyran-4-yl)-; 1159814-73-9; 5-(THP-4-yl)pyridin-2-amine; 5-(Tetrahydro-2H-pyran-4-yl)-2-aminopyridine
EINECS	Contact for details

Quality Control

Our 5-(Tetrahydro-2H-Pyran-4-Yl)Pyridin-2-Amine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via NMR and mass spectrometry, to ensure it meets the high standards required for pharmaceutical research. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms
Identification (IR)	Conforms
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.