Description

2-Bromo-5-(Piperidin-4-Yl)Pyridine is a high-value, multi-functional heterocyclic building block of significant interest in advanced organic synthesis. Its core value lies in its versatile reactivity, where the bromine atom serves as an excellent handle for cross-coupling reactions, and the piperidine moiety provides a key pharmacophore for modulating biological activity. This compound is primarily needed by research and development chemists in the pharmaceutical and agrochemical industries for the discovery and development of new active ingredients.

Application

• Pharmaceutical Intermediate: A key scaffold in the synthesis of small molecule drug candidates targeting central nervous system (CNS) disorders, oncology, and inflammation.
• Agrochemical Research: Used as a building block for developing novel active ingredients in crop protection and pest management solutions.
• Chemical Biology & Proteomics: Employed in the design and synthesis of molecular probes and tool compounds for studying biological pathways and protein function.
• Material Science Precursor: Serves as a monomer or functionalizing agent in the development of advanced polymers and organic electronic materials.
• Cross-Coupling Reactions: The bromine substituent makes it an ideal substrate for Suzuki, Stille, and Buchwald-Hartwig amination reactions to create complex biaryl and amine-containing structures.
• Library Synthesis for High-Throughput Screening: Used in parallel and combinatorial chemistry to generate diverse compound libraries for biological screening.

Basic Information

Product Name	2-Bromo-5-(Piperidin-4-Yl)Pyridine
CAS No.	1159814-58-0
Molecular Formula	C10H13BrN2
Molecular Weight	241.13 g/mol
Synonyms	4-(6-Bromopyridin-3-yl)piperidine; 5-(Piperidin-4-yl)-2-bromopyridine; 2-Bromo-5-(4-piperidinyl)pyridine; 6-Bromo-3-(4-piperidyl)pyridine; 2-Bromo-5-piperidin-4-ylpyridine; 1159814-58-0; 4-(6-Bromo-3-pyridinyl)piperidine
EINECS	Contact for details

Quality Control

Our 2-Bromo-5-(Piperidin-4-Yl)Pyridine is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity for research applications. Each lot undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to confirm identity and purity. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under a dry inert atmosphere to maintain stability and prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.