Description

Ethyl 1-Benzyl-5-Hydroxy-1,2,3,6-Tetrahydropyridine-4-Carboxylate Hydrochloride is a high-purity, synthetically derived organic salt serving as a critical advanced pharmaceutical intermediate. This compound matters for its role in the development of complex active pharmaceutical ingredients (APIs), where consistent quality and structural integrity are paramount. It is primarily needed by research institutions, pharmaceutical development laboratories, and fine chemical manufacturers engaged in the synthesis of novel therapeutic agents, particularly within the fields of neurology and metabolic disease research.

Application

• Pharmaceutical Intermediate: A key building block in the multi-step synthesis of complex drug candidates and active pharmaceutical ingredients (APIs).
• Medicinal Chemistry Research: Used in research and development for structure-activity relationship (SAR) studies and lead optimization.
• Process Chemistry Development: Serves as a standard or starting material for scaling up synthetic routes under Good Manufacturing Practice (GMP) conditions.
• Reference Standard: Employed as an analytical reference standard for quality control and method validation in pharmaceutical analysis.
• Academic Research: Utilized in university and institutional labs for studying heterocyclic chemistry and novel synthetic methodologies.
• Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for custom synthesis projects.

Basic Information

Item	Details
Product Name	Ethyl 1-Benzyl-5-Hydroxy-1,2,3,6-Tetrahydropyridine-4-Carboxylate Hydrochloride
CAS No.	1159694-57-1
Molecular Formula	C15H20ClNO3
Molecular Weight	297.78 g/mol
Synonyms	1-Benzyl-5-hydroxy-1,2,3,6-tetrahydropyridine-4-carboxylic acid ethyl ester hydrochloride; Ethyl 1-benzyl-5-hydroxy-3,6-dihydro-2H-pyridine-4-carboxylate hydrochloride; 4-Pyridinecarboxylic acid, 1,2,3,6-tetrahydro-5-hydroxy-1-benzyl-, ethyl ester, hydrochloride; 1-Benzyl-5-hydroxy-1,2,3,6-tetrahydro-4-pyridinecarboxylic Acid Ethyl Ester Hydrochloride; 1-Benzyl-5-hydroxypiperidine-4-carboxylate ethyl ester hydrochloride (tautomeric form); CAS 1159694-57-1
EINECS	Contact for details

Quality Control

Our Ethyl 1-Benzyl-5-Hydroxy-1,2,3,6-Tetrahydropyridine-4-Carboxylate Hydrochloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via IR and NMR spectroscopy, to ensure it meets the high standards required for pharmaceutical research and development. Certificates of Analysis (COA) detailing all test results are available upon request, providing full traceability and quality assurance.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after each use to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.