Description

Ethyl 3-(2-Fluorophenyl)-5-Methylisoxazole-4-Carboxylate is a high-purity fluorinated isoxazole derivative, a key synthetic intermediate valued for its structural complexity and reactivity. This compound is essential for research and development chemists seeking to introduce the biologically active isoxazole-fluorophenyl pharmacophore into novel molecular architectures. It is primarily utilized by pharmaceutical R&D laboratories and fine chemical manufacturers engaged in the synthesis of advanced agrochemicals and active pharmaceutical ingredients (APIs).

Application

• Pharmaceutical Intermediate: A critical building block in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders and anti-inflammatory pathways.
• Agrochemical Research: Serves as a precursor for developing new-generation herbicides and fungicides, leveraging the stability and bioactivity of the isoxazole ring.
• Material Science Chemistry: Used in the research and development of specialty chemicals, liquid crystals, and advanced polymeric materials.
• Academic & Contract Research: A valuable reagent for methodological studies in organic synthesis, including cross-coupling reactions and heterocyclic chemistry.
• Custom Synthesis: Employed by fine chemical suppliers for the contract manufacturing of complex, customer-specific molecules.

Basic Information

Product Name	Ethyl 3-(2-Fluorophenyl)-5-Methylisoxazole-4-Carboxylate
CAS No.	1159600-04-0
Molecular Formula	C13H12FNO3
Molecular Weight	249.24 g/mol
Synonyms	Ethyl 3-(2-fluorophenyl)-5-methyl-1,2-oxazole-4-carboxylate; 4-Carbethoxy-3-(2-fluorophenyl)-5-methylisoxazole; 5-Methyl-3-(2-fluorophenyl)isoxazole-4-carboxylic acid ethyl ester; 1159600-04-0; 3-(2-Fluorophenyl)-5-methyl-4-isoxazolecarboxylic acid ethyl ester; Ethyl 5-methyl-3-(2-fluorophenyl)isoxazole-4-carboxylate
EINECS	Contact for details

Quality Control

Our Ethyl 3-(2-Fluorophenyl)-5-Methylisoxazole-4-Carboxylate is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with every shipment, confirming compliance with customer specifications and industry best practices for fine chemical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep away from strong bases and incompatible organic solvents. The container should be kept tightly sealed to prevent moisture absorption and contamination.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Any single impurity	≤ 0.5%
Residual Solvents (GC)	Meets ICH Q3C guidelines
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.