Description

2-Bromo-3-Fluoro-6-(Trifluoromethyl)Pyridine is a high-value, multi-functional halogenated pyridine derivative, serving as a critical building block in advanced organic synthesis. Its unique substitution pattern makes it an indispensable intermediate for constructing complex molecules with tailored electronic and steric properties. This compound is primarily sought after by research and development teams in the pharmaceutical and agrochemical industries for creating novel active ingredients, as well as by manufacturers of specialty materials and electronic chemicals.

Application

• Pharmaceutical Intermediate: Key synthon for the development of active pharmaceutical ingredients (APIs), particularly in kinase inhibitors and central nervous system (CNS) targeted drugs.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and insecticides, leveraging the fluorine and trifluoromethyl groups for enhanced bioactivity and metabolic stability.
• Ligand & Catalyst Development: Serves as a precursor for creating novel nitrogen-containing ligands used in transition metal catalysis for cross-coupling and other fine chemical reactions.
• Material Science: Building block for organic electronic materials, such as charge-transport layers in OLEDs or semiconductors, due to its electron-deficient aromatic system.
• Chemical Research: A versatile reagent in academic and industrial R&D for exploring new heterocyclic chemistry and fluorination methodologies.
• Liquid Crystal & Dye Intermediates: Used in the synthesis of advanced functional dyes and liquid crystal compounds for display technologies.

Basic Information

Product Name	2-Bromo-3-Fluoro-6-(Trifluoromethyl)Pyridine
CAS No.	1159512-38-5
Molecular Formula	C6H2BrF4N
Molecular Weight	243.99 g/mol
Synonyms	2-Bromo-3-fluoro-6-(trifluoromethyl)pyridine; 3-Fluoro-2-bromo-6-(trifluoromethyl)pyridine; 6-(Trifluoromethyl)-3-fluoro-2-bromopyridine; Pyridine, 2-bromo-3-fluoro-6-(trifluoromethyl)-; 1159512-38-5
EINECS	Contact for details

Quality Control

Every batch of 2-Bromo-3-Fluoro-6-(Trifluoromethyl)Pyridine is manufactured and tested under strict quality management systems. We provide comprehensive analytical data to ensure the compound meets the high-purity standards required for sensitive synthetic applications. A detailed Certificate of Analysis (COA) is provided with each shipment, confirming identity, purity, and impurity profiles. Our quality commitment supports compliance with cGMP and ICH guidelines for pharmaceutical development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent moisture absorption and degradation. Keep away from incompatible materials such as strong bases and reducing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0% (Area %)
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.