Description

3-Bromo-2-Fluoro-6-(Trifluoromethyl)Pyridine is a high-value, multi-functional halogenated pyridine derivative that serves as a critical building block in advanced organic synthesis. Its unique structure, featuring bromine, fluorine, and a trifluoromethyl group on the pyridine ring, makes it an indispensable intermediate for creating complex molecules with tailored properties. This compound is primarily sought after by research and development teams in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key synthon for the development of active pharmaceutical ingredients (APIs), particularly in medicinal chemistry programs targeting CNS disorders, oncology, and anti-inflammatory agents.
• Agrochemical Synthesis: Used in the research and production of next-generation herbicides, fungicides, and insecticides, where the fluorine and trifluoromethyl groups enhance biological activity and environmental stability.
• Ligand and Catalyst Development: Serves as a precursor for synthesizing specialized ligands used in transition metal catalysis and cross-coupling reactions, such as Suzuki and Buchwald-Hartwig amination.
• Material Science Research: Employed in the creation of advanced organic electronic materials, including organic light-emitting diodes (OLEDs) and semiconductors, due to its electron-withdrawing characteristics.
• Chemical Biology Probes: Utilized as a building block for labeling reagents and molecular probes in biochemical and diagnostic research.
• Custom Synthesis and Contract Manufacturing: A vital starting material for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) serving the life sciences sector.

Basic Information

Product Name	3-Bromo-2-Fluoro-6-(Trifluoromethyl)Pyridine
CAS No.	1159512-36-3
Molecular Formula	C6H2BrF4N
Molecular Weight	243.99 g/mol
Synonyms	3-Bromo-2-fluoro-6-(trifluoromethyl)pyridine; 2-Fluoro-3-bromo-6-(trifluoromethyl)pyridine; 6-(Trifluoromethyl)-3-bromo-2-fluoropyridine; Pyridine, 3-bromo-2-fluoro-6-(trifluoromethyl)-; 1159512-36-3
EINECS	Contact for details

Quality Control

Our 3-Bromo-2-Fluoro-6-(Trifluoromethyl)Pyridine is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high purity and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing identity, assay, and impurity profiles. Our quality commitment ensures the material meets the stringent requirements for research and scale-up applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from heat, sparks, and open flame. The container should be kept tightly closed in a dry and well-ventilated place. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.