Description

3-Bromo-2-Chloro-6-(Trifluoromethyl)Pyridine is a high-value, multi-halogenated pyridine derivative that serves as a critical building block in advanced organic synthesis. Its unique structure, featuring bromine, chlorine, and trifluoromethyl substituents, makes it an indispensable intermediate for constructing complex molecules with tailored electronic and steric properties. This compound is primarily sought after by research chemists and process development scientists in the pharmaceutical and agrochemical industries for the development of new active ingredients.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of novel active pharmaceutical ingredients (APIs), particularly for kinase inhibitors and other small-molecule therapeutics.
• Agrochemical Synthesis: Used in the research and development of next-generation herbicides, fungicides, and insecticides, leveraging the bioactivity of the halogenated pyridine core.
• Material Science Research: Serves as a monomer or functionalization agent in the development of specialty polymers, liquid crystals, and electronic materials.
• Cross-Coupling Reactions: An excellent substrate for Suzuki, Stille, and Negishi cross-coupling reactions due to the reactive bromine substituent.
• Functional Group Transformation: Used in medicinal chemistry for parallel synthesis and library generation, allowing for the introduction of diverse functional groups.
• Chemical Biology Probes: Employed in the creation of molecular probes and tags for studying biological systems and target engagement.

Basic Information

Product Name	3-Bromo-2-Chloro-6-(Trifluoromethyl)Pyridine
CAS No.	1159512-34-1
Molecular Formula	C6H2BrClF3N
Molecular Weight	260.44 g/mol
Synonyms	2-Chloro-3-bromo-6-(trifluoromethyl)pyridine; 6-(Trifluoromethyl)-3-bromo-2-chloropyridine; 3-Bromo-2-chloro-6-trifluoromethylpyridine; Pyridine, 3-bromo-2-chloro-6-(trifluoromethyl)-; 1159512-34-1
EINECS	Contact for details

Quality Control

Every batch of 3-Bromo-2-Chloro-6-(Trifluoromethyl)Pyridine is manufactured and tested under a strict quality management system. We guarantee high chemical purity and lot-to-lot consistency, which is critical for reproducible research and scale-up processes. Our products undergo rigorous quality testing to ensure compliance with industry standards. Certificates of Analysis (COA) with detailed chromatographic data are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from strong bases and reducing agents. For long-term storage, consider storing under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Heavy Metals	< 20 ppm
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.