Description

2-Bromo-3-Chloroimidazo[1,2-A]Pyridine is a high-purity halogenated heterocyclic building block of significant importance in advanced organic synthesis. This compound matters as a key intermediate for constructing complex molecular architectures, particularly in the development of active pharmaceutical ingredients (APIs) and functional materials. It is primarily needed by research chemists and process development scientists in the pharmaceutical, agrochemical, and material science industries for lead optimization and scale-up activities.

Application

• Pharmaceutical Intermediate: A crucial precursor in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders, inflammation, and oncology.
• Agrochemical Research: Used in the development of new generation herbicides, fungicides, and insecticides, leveraging its unique heterocyclic core.
• Material Science: Serves as a building block for creating organic electronic materials, such as organic light-emitting diodes (OLEDs) and charge-transport molecules.
• Chemical Biology: Employed in the design and synthesis of molecular probes and tool compounds for studying biological pathways and protein function.
• Cross-Coupling Reactions: The bromo and chloro substituents make it an excellent substrate for versatile palladium-catalyzed cross-coupling reactions (e.g., Suzuki, Negishi, Buchwald-Hartwig).
• Library Synthesis: A valuable scaffold for generating diverse compound libraries in high-throughput screening and medicinal chemistry programs.

Basic Information

Item	Details
Product Name	2-Bromo-3-Chloroimidazo[1,2-A]Pyridine
CAS No.	1159511-19-9
Molecular Formula	C7H4BrClN2
Molecular Weight	231.48 g/mol
Synonyms	2-Bromo-3-chloroimidazo[1,2-a]pyridine; 3-Chloro-2-bromoimidazo[1,2-a]pyridine; Imidazo[1,2-a]pyridine, 2-bromo-3-chloro-; 1159511-19-9; 2-Bromo-3-chloro-imidazo[1,2-a]pyridine; 2-Bromo-3-chloroimidazo(1,2-a)pyridine
EINECS	Contact for details

Quality Control

Our 2-Bromo-3-Chloroimidazo[1,2-A]Pyridine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical specifications. Our quality commitment aligns with cGMP principles for advanced intermediates, ensuring reliability for your most demanding synthesis workflows.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). This material is light-sensitive and should be handled under appropriate conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.