Description

β-D-Mannopyranosyl Azide 3,4,6-Triacetate 2-(1,1,1-Trifluoromethanesulfonate) is a high-purity, advanced glycosyl donor building block designed for sophisticated organic synthesis. This compound is critical for researchers and manufacturers requiring precise, high-yielding glycosylation reactions to construct complex carbohydrate mimetics and glycoconjugates. It is primarily utilized in pharmaceutical R&D for the synthesis of novel drug candidates, particularly in antiviral, anticancer, and metabolic disease research, as well as in the development of specialized biochemical probes.

Application

• Pharmaceutical Intermediate: A key building block for the synthesis of complex oligosaccharides and glycoconjugates with potential therapeutic activity.
• Antiviral Drug Research: Used in the development of carbohydrate-based inhibitors targeting viral entry and replication mechanisms.
• Cancer Therapeutics: Employed in the construction of tumor-associated carbohydrate antigens (TACAs) for vaccine and antibody-drug conjugate (ADC) development.
• Chemical Biology & Probes: Serves as a precursor for "click chemistry" via the azide group, enabling the labeling and study of biological systems.
• Enzyme Inhibitor Synthesis: Facilitates the creation of glycosidase and glycosyltransferase inhibitors for metabolic pathway studies.
• Material Science: Potential use in creating specialized carbohydrate-based polymers and surfaces with unique bioactive properties.

Basic Information

Product Name	β-D-Mannopyranosyl Azide 3,4,6-Triacetate 2-(1,1,1-Trifluoromethanesulfonate)
CAS No.	1159265-99-2
Molecular Formula	C15H18F3N3O11S
Molecular Weight	505.38 g/mol
Synonyms	2-O-Trifluoromethanesulfonyl-3,4,6-tri-O-acetyl-β-D-mannopyranosyl azide; 3,4,6-Tri-O-acetyl-2-O-triflyl-β-D-mannopyranosyl azide; 2-O-Triflyl-3,4,6-tri-O-acetyl-β-D-mannopyranosyl azide; β-D-Mannosyl Azide Triflate Triacetate; Mannosyl Donor Triflate; Glycosyl Triflate Building Block; 1-Azido-3,4,6-tri-O-acetyl-2-O-((trifluoromethyl)sulfonyl)-β-D-mannopyranose
EINECS	Contact for details

Quality Control

Our β-D-Mannopyranosyl Azide 3,4,6-Triacetate 2-(1,1,1-Trifluoromethanesulfonate) is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including NMR (1H, 13C, 19F) and HPLC analysis, to ensure high chemical purity and structural integrity suitable for sensitive synthetic applications. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below under an inert atmosphere (e.g., argon or nitrogen) in a dedicated freezer for flammable materials. Allow the sealed container to equilibrate to room temperature before opening to minimize moisture ingress. Keep away from heat, sparks, and open flames.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95%
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.