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2-Deoxy-2-Fluoro-β-D-Glucopyranosyl Azide CAS NO 1159265-95-8
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CAS No.:1159265-95-8
Grade:Pharmacy Grade
Content:99.9%
Brand:Customizable
Packaging:Customizable
Description
2-Deoxy-2-Fluoro-β-D-Glucopyranosyl Azide is a high-value fluorinated carbohydrate derivative, serving as a critical building block in advanced organic synthesis. Its unique structure, featuring both a fluorine atom and an azide group, makes it an essential precursor for the development of novel bioactive molecules and diagnostic agents. This compound is primarily sought after by researchers and process chemists in the pharmaceutical, biotechnology, and diagnostic imaging sectors for creating targeted glycosidase inhibitors and PET (Positron Emission Tomography) tracers.
Application
- Pharmaceutical Intermediate: Key precursor in the synthesis of fluorinated glycomimetics and glycosidase inhibitors for therapeutic development.
- PET Tracer Synthesis: Used in the radiochemical synthesis of fluorine-18 (18F) labeled probes for diagnostic imaging in oncology and neurology.
- Chemical Biology Tool: Employed in click chemistry (e.g., CuAAC) for bioconjugation and labeling of biomolecules due to its reactive azide group.
- Glycochemistry Research: Fundamental building block for studying carbohydrate-protein interactions and enzyme mechanisms.
- Agrochemical Development: Intermediate in the research and synthesis of novel fluorinated active ingredients.
Basic Information
| Product Name | 2-Deoxy-2-Fluoro-β-D-Glucopyranosyl Azide |
| CAS No. | 1159265-95-8 |
| Molecular Formula | C6H10FN3O4 |
| Molecular Weight | 207.16 g/mol |
| Synonyms | 2-Deoxy-2-fluoro-β-D-glucopyranosyl azide; 2-Fluoro-2-deoxy-β-D-glucopyranosyl azide; β-D-Glucopyranosyl azide, 2-deoxy-2-fluoro-; 1-Azido-2-deoxy-2-fluoro-β-D-glucopyranose; 2-Fluoro-2-deoxyglucosyl azide; FDG Azide Precursor; 2-FDG Azide; Azido-2-fluoro-2-deoxyglucose |
| EINECS | Contact for details |
Quality Control
Every batch of 2-Deoxy-2-Fluoro-β-D-Glucopyranosyl Azide is manufactured and tested under strict quality management systems. We provide comprehensive analytical data to ensure identity, purity, and consistency for your critical research and development processes. A Certificate of Analysis (COA) detailing specifications such as assay (by HPLC), optical rotation, and impurity profile is supplied with each shipment.
Storage
Preserve in a tightly closed container, protected from light. Store at 2-8°C under an inert atmosphere (e.g., nitrogen or argon) to prevent oxidation and degradation. The material is moisture-sensitive; keep the container tightly sealed in a cool, dry, and well-ventilated place.
Specification
| Item | Specification |
|---|---|
| Appearance | White to off-white solid |
| Identification (IR) | Conforms to structure |
| Identification (NMR) | Conforms to structure |
| Assay (HPLC) | ≥ 95.0% |
| Optical Rotation | Contact for details |
| Water Content (KF) | ≤ 1.0% |
| Residual Solvents (GC) | Meets ICH guidelines |
Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.
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