Description

2',3'-Dihydro-1'H-Spiro[Cyclopropane-1,4'-Isoquinoline] is a high-value, spirocyclic organic compound featuring a fused isoquinoline and cyclopropane ring system. This unique molecular architecture makes it a critical advanced pharmaceutical intermediate (API) and a versatile building block for medicinal chemistry research. It is primarily utilized by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and fine chemical industries for the synthesis of novel bioactive molecules and complex heterocycles.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of potential drug candidates targeting central nervous system (CNS) disorders, oncology, and other therapeutic areas.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and library synthesis for the discovery of new chemical entities.
• Agrochemical Development: Serves as a precursor for creating novel active ingredients with potential insecticidal or herbicidal properties.
• Ligand and Catalyst Synthesis: Employed in the development of specialized ligands for asymmetric catalysis or metal-organic frameworks (MOFs).
• Fine Chemical Synthesis: A versatile scaffold for constructing complex spirocyclic and polycyclic compounds in custom synthesis projects.
• Academic & Institutional Research: Used in universities and research institutes for fundamental studies in organic synthesis and heterocyclic chemistry.

Basic Information

Product Name	2',3'-Dihydro-1'H-Spiro[Cyclopropane-1,4'-Isoquinoline]
CAS No.	1159010-39-5
Molecular Formula	C11H11N
Molecular Weight	157.21 g/mol
Synonyms	1'H-Spiro[cyclopropane-1,4'-isoquinoline], 2',3'-Dihydro-; 2,3-Dihydro-1H-spiro[cyclopropane-1,4'-isoquinoline]; Spiro[cyclopropane-1,4'-isoquinoline], 2',3'-dihydro-; 1159010-39-5; 2,3-Dihydrospiro[cyclopropane-1,1'-isoquinoline]; Spirocyclic isoquinoline derivative; Cyclopropane-spiro-isoquinoline
EINECS	Contact for details

Quality Control

Our 2',3'-Dihydro-1'H-Spiro[Cyclopropane-1,4'-Isoquinoline] is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and MS, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided with every shipment. We support cGMP compliance for pharmaceutical applications and can tailor purity grades to meet specific project requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) to prevent moisture absorption and degradation. Keep away from heat and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.