Description

3-Methyl-Tetrahydrofuran-3-Carboxylic Acid is a versatile chiral building block and intermediate of significant interest in advanced organic synthesis. Its unique structure, featuring both a tetrahydrofuran ring and a carboxylic acid functional group, makes it a valuable precursor for constructing complex molecules with precise stereochemistry. This compound is primarily utilized by research institutions and manufacturers in the pharmaceutical and agrochemical industries for the development of active ingredients and novel chemical entities.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the synthesis of active pharmaceutical ingredients (APIs), particularly in the development of central nervous system (CNS) drugs and antiviral agents.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and insecticides that require specific stereochemical configurations for optimal activity.
• Ligand and Catalyst Development: Serves as a precursor for creating novel chiral ligands and organocatalysts used in asymmetric synthesis.
• Fine Chemical Production: Employed in the manufacture of specialty chemicals, flavors, and fragrances where high purity and specific isomerism are critical.
• Academic and R&D: A valuable compound for methodological research in organic chemistry, including studies on ring-forming reactions and stereoselective transformations.
• Material Science Precursor: Potential use in the synthesis of functionalized polymers and advanced materials with tailored properties.

Basic Information

Product Name	3-Methyl-Tetrahydrofuran-3-Carboxylic Acid
CAS No.	1158760-45-2
Molecular Formula	C7H10O3
Molecular Weight	142.15 g/mol
Synonyms	3-Methyloxolane-3-carboxylic acid; 3-Methyltetrahydrofuran-3-carboxylic acid; 3-Carboxy-3-methyltetrahydrofuran; 3-Methyl-3-tetrahydrofurancarboxylic acid; 3-Methyl-3-carboxytetrahydrofuran; Tetrahydro-3-methyl-3-furancarboxylic acid; (Tetrahydro-3-methyl-3-furyl)carboxylic acid
EINECS	Contact for details

Quality Control

Our 3-Methyl-Tetrahydrofuran-3-Carboxylic Acid is produced under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, chiral analysis for enantiomeric excess, and standard identification tests, to ensure it meets the high standards required for research and commercial synthesis. Certificates of Analysis (COA) with detailed chromatographic data are provided for every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture. For long-term storage, consider the use of desiccants.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% e.e.
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals (as Pb)	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.