Description

1-Azetidinecarboxylic Acid, 3-(Aminomethyl)-3-Methyl-, 1,1-Dimethylethyl Ester is a high-purity, protected azetidine derivative of significant interest in advanced organic synthesis. This compound serves as a critical pharmaceutical intermediate and building block for the development of novel bioactive molecules. It is primarily needed by research institutions and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: A key chiral building block for the synthesis of active pharmaceutical ingredients (APIs), particularly in the development of protease inhibitors and other therapeutic agents.
• Agrochemical Synthesis: Used in the research and production of novel pesticides and herbicides, leveraging its constrained azetidine ring structure.
• Peptidomimetics & Drug Discovery: The protected amino acid structure makes it invaluable for creating peptide analogs and exploring structure-activity relationships in medicinal chemistry.
• Ligand & Catalyst Development: Serves as a precursor for designing novel chiral ligands and organocatalysts used in asymmetric synthesis.
• Chemical Biology Research: Employed as a molecular probe or scaffold in biochemical studies to investigate enzyme mechanisms and protein interactions.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for the production of client-specific target molecules.

Basic Information

Item	Detail
Product Name	1-Azetidinecarboxylic Acid, 3-(Aminomethyl)-3-Methyl-, 1,1-Dimethylethyl Ester
CAS No.	1158758-85-0
Molecular Formula	C10H20N2O2
Molecular Weight	200.28 g/mol
Synonyms	tert-Butyl 3-(aminomethyl)-3-methylazetidine-1-carboxylate; 3-(Aminomethyl)-3-methylazetidine-1-carboxylic acid tert-butyl ester; Boc-3-(aminomethyl)-3-methylazetidine; 1-Boc-3-(aminomethyl)-3-methylazetidine; 3-Methyl-3-(aminomethyl)azetidine-1-carboxylic acid tert-butyl ester; (3-Methyl-3-azetidinylmethyl)carbamic acid tert-butyl ester; Azetidine-1-carboxylic acid, 3-(aminomethyl)-3-methyl-, 1,1-dimethylethyl ester
EINECS	Contact for details

Quality Control

Our 1-Azetidinecarboxylic Acid, 3-(Aminomethyl)-3-Methyl-, 1,1-Dimethylethyl Ester is produced under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure high purity and consistency, meeting the stringent requirements for advanced synthetic applications. Certificates of Analysis (COA) with detailed chromatographic and spectroscopic data are provided to guarantee traceability and compliance with your specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0% (Area %)
Water Content (KF)	≤ 0.5% w/w
Residue on Ignition	≤ 0.1%
Heavy Metals (as Pb)	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.