Description

1,9-Diazaspiro[5.5]Undecan-1-Carboxylic Acid tert-Butyl Ester is a high-value, protected spirocyclic amine building block essential for modern pharmaceutical and agrochemical research. This compound serves as a critical intermediate in the synthesis of complex molecules, offering a rigid, three-dimensional scaffold that can significantly influence the biological activity and pharmacokinetic properties of the final product. It is primarily utilized by medicinal chemists and process development scientists in the pharmaceutical industry for the development of new therapeutic agents.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel active pharmaceutical ingredients (APIs), particularly for central nervous system (CNS) and anti-infective drug candidates.
• Medicinal Chemistry Scaffold: Used to introduce a constrained, spirocyclic amine moiety into lead compounds to optimize potency, selectivity, and metabolic stability.
• Agrochemical Research: Employed in the development of new herbicides, fungicides, and insecticides where the spirocyclic structure can confer unique biological activity.
• Chemical Biology Probes: Serves as a precursor for designing molecular probes to study enzyme function and biological pathways.
• Process Chemistry: Used in route scouting and scale-up processes for the commercial manufacturing of complex organic molecules.
• Custom Synthesis & Contract Manufacturing: A critical starting material for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) serving the global life sciences market.

Basic Information

Product Name	1,9-Diazaspiro[5.5]Undecan-1-Carboxylic Acid tert-Butyl Ester
CAS No.	1158750-00-5
Molecular Formula	C14H26N2O2
Molecular Weight	254.37 g/mol
Synonyms	tert-Butyl 1,9-diazaspiro[5.5]undecane-1-carboxylate; 1,9-Diazaspiro[5.5]undecane-1-carboxylic acid, 1,1-dimethylethyl ester; 1-Boc-1,9-diazaspiro[5.5]undecane; 1-N-Boc-1,9-diazaspiro[5.5]undecane; Spirocyclic Amine Boc Ester; 1,9-Diazaspiro[5.5]undecan-1-carboxylic acid tert-butyl ester; 1-(tert-Butoxycarbonyl)-1,9-diazaspiro[5.5]undecane
EINECS	Contact for details

Quality Control

Our 1,9-Diazaspiro[5.5]Undecan-1-Carboxylic Acid tert-Butyl Ester is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing to ensure high purity and consistency, meeting the stringent requirements for pharmaceutical R&D and process chemistry. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are provided with each shipment and are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). This material is moisture-sensitive; keep the container tightly sealed under an inert atmosphere (e.g., nitrogen or argon) for long-term storage to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.