Description

1,9-Diazaspiro[5.5]Undecan-2-One CAS NO 1158749-97-3 is a high-purity, nitrogen-containing heterocyclic compound belonging to the spirocyclic lactam class. This versatile building block is critical for advanced pharmaceutical research and development, particularly in the synthesis of complex active pharmaceutical ingredients (APIs). It is primarily utilized by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and fine chemical industries seeking to introduce novel spirocyclic frameworks into their molecular designs.

Application

• Pharmaceutical Intermediate: A key synthetic precursor in the development of novel drug candidates, particularly for central nervous system (CNS) and metabolic disorder targets.
• Spirocyclic Scaffold Synthesis: Serves as a privileged scaffold for constructing complex, three-dimensional molecular architectures with improved pharmacological properties.
• Ligand and Receptor Binder Development: Used in medicinal chemistry to create new ligands for biological target validation and hit-to-lead optimization.
• Agrochemical Research: Employed as a building block for developing new crop protection agents and pesticides with novel modes of action.
• Chemical Biology Probes: Utilized in the synthesis of specialized probes for studying enzyme function and protein-protein interactions.
• Academic and Contract Research: A valuable reagent for universities and CROs (Contract Research Organizations) engaged in synthetic methodology and heterocyclic chemistry research.

Basic Information

Product Name	1,9-Diazaspiro[5.5]Undecan-2-One
CAS No.	1158749-97-3
Molecular Formula	C9H14N2O
Molecular Weight	166.22 g/mol
Synonyms	1,9-Diazaspiro[5.5]undecan-2-one; 2-Oxo-1,9-diazaspiro[5.5]undecane; 1,9-Diazaspiro[5.5]undecane-2-one; Spiro[piperidine-4,2'-pyrrolidin]-3-one; 2-Azaspiro[4.5]decane-1,3-dione derivative (related structure); 9-Azaspiro[5.5]undecan-10-one (tautomeric form); 1,9-Diazaspiro[5.5]undecanone
EINECS	Contact for details

Quality Control

Our 1,9-Diazaspiro[5.5]Undecan-2-One is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and residual solvent analysis to ensure it meets the high standards required for research and development applications. Certificates of Analysis (COA) with detailed chromatograms and spectral data are provided for every shipment to guarantee traceability and consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to prevent moisture absorption, which may affect stability and handling properties. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Meets ICH Q3C guidelines
Heavy Metals	< 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.