Description

(6-Oxopyrazolo[5,1-C]Pyrido[4,3-E][1,2,4]Triazin-7(6H)-Yl)Acetic Acid is a high-purity, advanced pharmaceutical intermediate with a complex heterocyclic structure. This compound is of significant value in medicinal chemistry for the research and development of novel therapeutic agents, particularly as a key building block in kinase inhibitor synthesis. It is primarily needed by pharmaceutical R&D laboratories, biotechnology companies, and contract research organizations (CROs) focused on oncology, inflammation, and other targeted therapy areas.

Application

• Pharmaceutical Intermediate: Serves as a critical precursor in the multi-step synthesis of potent kinase inhibitors and other small molecule drug candidates.
• Medicinal Chemistry Research: Used as a scaffold or building block for structure-activity relationship (SAR) studies to optimize drug potency and selectivity.
• Biochemical Probe Development: Utilized in the creation of chemical probes for studying specific enzyme pathways and biological targets in disease models.
• Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for cGMP production of active pharmaceutical ingredients (APIs) in clinical trials.
• Academic Research: Employed in university and institutional labs for fundamental research in heterocyclic chemistry and drug discovery methodologies.

Basic Information

Product Name	(6-Oxopyrazolo[5,1-C]Pyrido[4,3-E][1,2,4]Triazin-7(6H)-Yl)Acetic Acid
CAS No.	1158405-49-2
Molecular Formula	C₁₁H₇N₅O₃
Molecular Weight	257.21 g/mol
Synonyms	7H-Pyrazolo[5,1-c][1,2,4]triazine-7-acetic acid, 4,6-dihydro-6-oxo-; (6-Oxo-4,6-dihydropyrazolo[5,1-c][1,2,4]triazin-7-yl)acetic acid; 1158405-49-2; Pyrazolotriazine acetic acid derivative; 6-Oxo-6,7-dihydropyrazolo[5,1-c][1,2,4]triazine-7-acetic acid
EINECS	Contact for details

Quality Control

Our (6-Oxopyrazolo[5,1-C]Pyrido[4,3-E][1,2,4]Triazin-7(6H)-Yl)Acetic Acid is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via NMR and mass spectrometry, to ensure it meets the stringent requirements for pharmaceutical R&D. A comprehensive Certificate of Analysis (COA) detailing purity, impurities, and analytical methods is provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (typically 15-25°C). The compound may be light-sensitive and should be handled under appropriate conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms to reference standard
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.