Description

4-Bromo-2-Chloro-5-Nitro-Benzoic Acid Methyl Ester is a high-purity, multi-functional chemical intermediate essential for advanced organic synthesis. Its unique halogenated and nitrated benzoate structure makes it a critical building block for constructing complex molecules with specific electronic and steric properties. This compound is primarily sought after by research and development teams in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for molecules requiring halogenated aromatic cores.
• Agrochemical Synthesis: Used in the research and development of new herbicides, fungicides, and pesticides, leveraging its reactive sites for further functionalization.
• Material Science Research: Serves as a monomer or building block for creating specialized polymers, liquid crystals, or organic electronic materials.
• Dye and Pigment Intermediate: Employed in the development of novel colorants and photographic chemicals due to its nitro and ester functionalities.
• Cross-Coupling Reactions: An excellent substrate for palladium-catalyzed reactions like Suzuki, Stille, or Buchwald-Hartwig amination, enabling complex bond formation.
• Academic and Contract Research: A valuable reagent for methodological studies and synthetic route exploration in university and CRO laboratories.

Basic Information

Product Name	4-Bromo-2-Chloro-5-Nitro-Benzoic Acid Methyl Ester
CAS No.	1157672-86-0
Molecular Formula	C8H5BrClNO4
Molecular Weight	294.49 g/mol
Synonyms	Methyl 4-Bromo-2-Chloro-5-Nitrobenzoate; Benzoic acid, 4-bromo-2-chloro-5-nitro-, methyl ester; 4-Bromo-2-chloro-5-nitrobenzoic acid methyl ester; Methyl 4-bromo-2-chloro-5-nitrobenzoate; 2-Chloro-4-bromo-5-nitrobenzoic acid methyl ester
EINECS	Contact for details

Quality Control

Our 4-Bromo-2-Chloro-5-Nitro-Benzoic Acid Methyl Ester is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all relevant specifications. Our quality commitment ensures the material meets the stringent requirements for research and scale-up applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (typically 15-25°C). Keep away from heat, sparks, and open flame. The container should be kept tightly sealed to prevent moisture absorption and contamination.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Impurity (HPLC)	≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.