Description

(2-Chloro-Pyridin-3-Yl)-(3-Hydroxymethyl-Piperidin-1-Yl)-Methanone is a high-purity, synthetically valuable organic building block. This compound is a key intermediate in the development of advanced pharmaceutical agents, particularly in medicinal chemistry research. It is primarily sought after by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and fine chemical industries for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: Serves as a critical precursor in the synthesis of novel active pharmaceutical ingredients (APIs), especially for central nervous system (CNS) and anti-infective drug candidates.
• Medicinal Chemistry Research: Used as a versatile scaffold for structure-activity relationship (SAR) studies and lead optimization in drug discovery programs.
• Agrochemical Synthesis: Employed in the research and development of new generation pesticides and herbicides, leveraging its heterocyclic structure.
• Ligand and Catalyst Development: Acts as a starting material for creating specialized ligands used in asymmetric catalysis and metal-organic frameworks (MOFs).
• Fine Chemical Production: Utilized in the custom synthesis of complex, high-value specialty chemicals for various industrial applications.

Basic Information

Product Name	(2-Chloro-Pyridin-3-Yl)-(3-Hydroxymethyl-Piperidin-1-Yl)-Methanone
CAS No.	1156804-89-5
Molecular Formula	C12H15ClN2O2
Molecular Weight	254.71 g/mol
Synonyms	1-(2-Chloropyridine-3-carbonyl)-3-piperidinemethanol; 3-Piperidinemethanol, 1-(2-chloro-3-pyridinyl)carbonyl]-; (2-Chloro-3-pyridinyl)(3-hydroxymethyl-1-piperidinyl)methanone; 2-Chloro-N-(3-hydroxy-1-piperidinyl)nicotinamide; 2-Chloronicotinic acid 3-hydroxymethylpiperidide; Building Block 1156804-89-5; 2-Chloro-3-(3-hydroxymethylpiperidine-1-carbonyl)pyridine
EINECS	Contact for details

Quality Control

Our (2-Chloro-Pyridin-3-Yl)-(3-Hydroxymethyl-Piperidin-1-Yl)-Methanone is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide Certificates of Analysis (COA) with every shipment, detailing all critical quality attributes. Our production adheres to cGMP guidelines where applicable, ensuring reliability for research and scale-up processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to exclude moisture. For long-term storage, consider using desiccants or an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.