Description

2-Bromo-4-Chloro-3-Fluoropyridine is a high-purity halogenated pyridine derivative, serving as a critical building block in advanced organic synthesis. Its unique substitution pattern makes it an invaluable intermediate for constructing complex molecules with tailored properties. This compound is primarily sought after by research and development teams in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key synthon for the development of active pharmaceutical ingredients (APIs), particularly in medicinal chemistry programs targeting new therapeutic agents.
• Agrochemical Synthesis: Used in the research and production of advanced crop protection agents, including herbicides, fungicides, and insecticides.
• Material Science Research: Serves as a precursor for the synthesis of functionalized ligands, liquid crystals, and other specialty organic materials.
• Chemical Biology: Employed as a versatile building block for creating molecular probes and biochemical tools.
• Cross-Coupling Reactions: An effective substrate for Suzuki, Stille, and other palladium-catalyzed cross-coupling reactions to form complex biaryl structures.
• Nucleophilic Substitution: The halogen atoms provide reactive sites for further functionalization via nucleophilic aromatic substitution.

Basic Information

Product Name	2-Bromo-4-Chloro-3-Fluoropyridine
CAS No.	1155847-42-9
Molecular Formula	C5H2BrClFN
Molecular Weight	210.43 g/mol
Synonyms	3-Fluoro-2-bromo-4-chloropyridine; 4-Chloro-3-fluoro-2-bromopyridine; 2-Bromo-4-chloro-3-fluoropyridine; Pyridine, 2-bromo-4-chloro-3-fluoro-; 1155847-42-9; BCFP; 2-Br-4-Cl-3-F-Pyridine
EINECS	Contact for details

Quality Control

Every batch of 2-Bromo-4-Chloro-3-Fluoropyridine is manufactured under strict quality management protocols. Our products undergo rigorous analytical testing, including HPLC, GC, and NMR, to ensure high purity and batch-to-batch consistency. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment to support your quality assurance and regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, containers should be kept in the original packaging or an opaque secondary container until use.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Maximum Impurity (HPLC)	≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.