Description

4-(4-Hydroxypiperidine-1-Carbonyl)-1-Methyl-1,2-Dihydropyridin-2-One is a high-purity, advanced pharmaceutical intermediate with a complex heterocyclic structure. This compound is critical for the synthesis of novel active pharmaceutical ingredients (APIs), particularly in therapeutic areas requiring sophisticated molecular scaffolds. It is primarily utilized by research institutions and pharmaceutical manufacturers engaged in the development of new drug candidates, especially within oncology and central nervous system (CNS) research.

Application

• Pharmaceutical Intermediate: Serves as a key building block in the synthesis of complex drug molecules and novel active pharmaceutical ingredients (APIs).
• Medicinal Chemistry Research: Used in lead optimization and structure-activity relationship (SAR) studies for new therapeutic agents.
• Oncology Drug Development: A potential precursor for kinase inhibitors and other targeted cancer therapies.
• CNS Drug Discovery: Employed in the research and development of neurological and psychiatric disorder treatments.
• Contract Research & Manufacturing (CRO/CMO): Supplied to organizations specializing in custom synthesis and process development.
• Academic Research: Used in university and institutional labs for chemical biology and synthetic methodology studies.

Basic Information

Product Name	4-(4-Hydroxypiperidine-1-Carbonyl)-1-Methyl-1,2-Dihydropyridin-2-One
CAS No.	1155607-95-6
Molecular Formula	C12H16N2O3
Molecular Weight	236.27 g/mol
Synonyms	1-Methyl-4-(4-hydroxypiperidine-1-carbonyl)-1,2-dihydropyridin-2-one; 4-(4-Hydroxy-1-piperidinyl)carbonyl-1-methyl-2(1H)-pyridinone; 1-Methyl-2-oxo-1,2-dihydropyridine-4-carboxylic acid (4-hydroxypiperidin-1-yl)amide; 1155607-95-6; 4-(4-Hydroxypiperidin-1-yl)-1-methyl-2-oxo-1,2-dihydropyridine-3-carboxamide (tautomeric form); 1-Methyl-4-[(4-hydroxypiperidin-1-yl)carbonyl]pyridin-2(1H)-one
EINECS	Contact for details

Quality Control

Our 4-(4-Hydroxypiperidine-1-Carbonyl)-1-Methyl-1,2-Dihydropyridin-2-One is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specifications and test results. Our commitment to quality supports compliance with cGMP and ICH guidelines for pharmaceutical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (typically 15-25°C). Keep away from incompatible materials. For long-term storage, consider inert atmosphere conditions to ensure stability.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC)	Conforms
Identification (IR)	Conforms
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.