Description

8-Ethoxy-2,3,4,5-Tetrahydropyrido[3,2-F][1,4]Oxazepine Hydrochloride is a high-purity, advanced pharmaceutical intermediate belonging to the oxazepine class of heterocyclic compounds. This compound is critical for research and development in medicinal chemistry, particularly for its role as a key building block in synthesizing novel therapeutic agents. It is primarily utilized by pharmaceutical R&D laboratories, contract research organizations (CROs), and fine chemical manufacturers targeting the development of central nervous system (CNS) and other bioactive molecules.

Application

• Pharmaceutical Intermediate: Serves as a crucial precursor in the multi-step synthesis of potential drug candidates, especially those targeting neurological pathways.
• Medicinal Chemistry Research: Used as a scaffold or building block for structure-activity relationship (SAR) studies and lead optimization in drug discovery programs.
• Reference Standard: Employed as an analytical standard for method development, validation, and quality control in API (Active Pharmaceutical Ingredient) manufacturing.
• Biochemical Research: Utilized in vitro studies to investigate interactions with biological targets such as receptors or enzymes.
• Process Chemistry Development: Acts as a key material for scaling up and optimizing synthetic routes under Good Manufacturing Practice (GMP) conditions.
• Academic Research: Used in university and institutional labs for exploring new synthetic methodologies and heterocyclic chemistry.

Basic Information

Item	Detail
Product Name	8-Ethoxy-2,3,4,5-Tetrahydropyrido[3,2-F][1,4]Oxazepine Hydrochloride
CAS No.	1154473-06-9
Molecular Formula	C12H17ClN2O2
Molecular Weight	256.73 g/mol
Synonyms	8-Ethoxy-2,3,4,5-tetrahydro-1,5-benzoxazocine Hydrochloride; 8-Ethoxy-2,3,4,5-tetrahydro-1H-pyrido[3,2-f][1,4]oxazepine hydrochloride; UNII-5V8Q1N95JN; 5V8Q1N95JN; 1,4-Oxazepine, 8-ethoxy-2,3,4,5-tetrahydro-, hydrochloride, (3,2-f)pyrido-; 8-Ethoxy-2,3,4,5-tetrahydro-1H-pyrido[3,2-f][1,4]oxazepine monohydrochloride
EINECS	Contact for details

Quality Control

Our 8-Ethoxy-2,3,4,5-Tetrahydropyrido[3,2-F][1,4]Oxazepine Hydrochloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and tests for residual solvents and heavy metals to ensure it meets the stringent requirements for pharmaceutical research. A comprehensive Certificate of Analysis (COA) is provided with every shipment, detailing all specifications and test results.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed in a dry environment to prevent moisture absorption, which may affect stability and handling properties. For long-term storage, consider desiccants or inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Residual Solvents (GC)	Complies with ICH Q3C guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.