Description

Pyrido[3,2-F]-1,4-Oxazepine-4(5H)-Carboxylic Acid, 8-Ethoxy-2,3-Dihydro-, 1,1-Dimethylethyl Ester is a high-value, complex heterocyclic building block designed for advanced pharmaceutical and agrochemical research. This compound is critical for medicinal chemists seeking to develop novel small-molecule therapeutics, particularly in central nervous system (CNS) and oncology targets, due to its unique fused oxazepine-pyridine scaffold. It is primarily utilized by R&D laboratories and process development teams in the pharmaceutical and fine chemical industries for lead optimization and synthesis of active pharmaceutical ingredients (APIs).

Application

• Pharmaceutical Intermediate: A key synthetic precursor in the development of novel drug candidates, particularly for neurological disorders and cancer therapies.
• Medicinal Chemistry Research: Used as a sophisticated scaffold for structure-activity relationship (SAR) studies and lead compound optimization.
• Process Chemistry Development: Serves as a critical intermediate in the scale-up and route scouting for potential Active Pharmaceutical Ingredients (APIs).
• Agrochemical Synthesis: Employed in the research and development of new generation pesticides and herbicides, leveraging its heterocyclic structure.
• Academic & Institutional Research: Used in universities and research institutes for studying heterocyclic chemistry and developing new synthetic methodologies.
• Custom Synthesis & Contract Manufacturing: A vital building block for CDMOs (Contract Development and Manufacturing Organizations) offering bespoke chemical synthesis services.

Basic Information

Product Name	Pyrido[3,2-F]-1,4-Oxazepine-4(5H)-Carboxylic Acid, 8-Ethoxy-2,3-Dihydro-, 1,1-Dimethylethyl Ester
CAS No.	1154471-53-0
Molecular Formula	C15H20N2O4
Molecular Weight	292.33 g/mol
Synonyms	tert-Butyl 8-ethoxy-2,3-dihydro-5H-pyrido[3,2-f][1,4]oxazepine-4(5H)-carboxylate; 8-Ethoxy-2,3-dihydro-5H-pyrido[3,2-f][1,4]oxazepine-4-carboxylic acid tert-butyl ester; 1,1-Dimethylethyl 8-ethoxy-2,3-dihydro-5H-pyrido[3,2-f][1,4]oxazepine-4-carboxylate; Pyrido-oxazepine tert-butyl ester; CAS 1154471-53-0; 8-Ethoxy-DHPO-CBz tert-butyl ester
EINECS	Contact for details

Quality Control

Our production of Pyrido[3,2-F]-1,4-Oxazepine-4(5H)-Carboxylic Acid, 8-Ethoxy-2,3-Dihydro-, 1,1-Dimethylethyl Ester adheres to stringent quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and residual solvent analysis by GC. Certificates of Analysis (COA) detailing all specifications are provided and can be tailored to meet specific client or regulatory requirements, supporting development under cGMP guidelines where applicable.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). This material may be hygroscopic (moisture-sensitive); keep the container tightly sealed under an inert atmosphere if specified. Keep away from heat and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Related Substances (HPLC)	Total impurities ≤ 3.0%
Any single unknown impurity	≤ 0.5%
Residual Solvents (GC)	Complies with ICH Q3C guidelines
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.