Description

4-[4-(Aminomethyl)Pyridin-2-Yl]-1Lambda(6),4-Thiomorpholine-1,1-Dione is a high-purity, advanced pharmaceutical intermediate characterized by its unique heterocyclic structure combining pyridine and thiomorpholine moieties. This compound is of significant commercial value for its role as a critical building block in the synthesis of novel active pharmaceutical ingredients (APIs). It is primarily sought after by research institutions and pharmaceutical manufacturers engaged in the development of new therapeutic agents, particularly within oncology and central nervous system (CNS) drug discovery pipelines.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of complex drug candidates, especially for targeted cancer therapies and neurological disorders.
• Research & Development (R&D): Used in medicinal chemistry for structure-activity relationship (SAR) studies and lead optimization in drug discovery programs.
• Chemical Synthesis: Serves as a versatile building block for constructing novel heterocyclic compounds in organic and process chemistry.
• Bioconjugation: The aminomethyl group provides a handle for conjugation, useful in developing antibody-drug conjugates (ADCs) or diagnostic probes.
• Agrochemical Research: Potential application as an intermediate in the development of new crop protection agents with novel modes of action.

Basic Information

Product Name	4-[4-(Aminomethyl)Pyridin-2-Yl]-1Lambda(6),4-Thiomorpholine-1,1-Dione
CAS No.	1153843-40-3
Molecular Formula	C11H15N3O2S
Molecular Weight	253.32 g/mol
Synonyms	4-[4-(Aminomethyl)pyridin-2-yl]-1λ⁶,4-thiomorpholine-1,1-dione; 4-(4-(Aminomethyl)pyridin-2-yl)thiomorpholine 1,1-dioxide; 2-(1,1-Dioxido-1,4-thiazinan-4-yl)-4-pyridinemethanamine; 4-(4-(Aminomethyl)-2-pyridinyl)thiomorpholine 1,1-dioxide; 1153843-40-3; Aminomethyl-pyridinyl-thiomorpholine dioxide; Thiomorpholine dioxide derivative
EINECS	Contact for details

Quality Control

Our production of 4-[4-(Aminomethyl)Pyridin-2-Yl]-1Lambda(6),4-Thiomorpholine-1,1-Dione adheres to stringent quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and residual solvent analysis by GC. We provide a detailed Certificate of Analysis (COA) with each shipment, ensuring traceability and compliance with cGMP guidelines for pharmaceutical intermediates. Our commitment is to deliver consistent high-purity material to support your critical R&D and scale-up activities.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to minimize exposure to atmospheric moisture. For long-term storage, consider using desiccants or storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Meets ICH Q3C guidelines
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.