Description

2-Pyridinamine, 6-Chloro-3-Nitro-n-(Tetrahydro-2H-Pyran-4-Yl)- is a high-purity, advanced pharmaceutical intermediate characterized by its specific pyridine and tetrahydropyran substitution pattern. This compound is of significant value for its role as a key building block in the synthesis of complex, biologically active molecules, particularly in medicinal chemistry. It is primarily needed by research institutions and pharmaceutical companies engaged in the development of new active pharmaceutical ingredients (APIs) and agrochemicals.

Application

• Pharmaceutical Intermediate: Serves as a critical precursor in the multi-step synthesis of novel drug candidates, especially those targeting central nervous system (CNS) disorders and other therapeutic areas.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization processes to develop compounds with improved efficacy and pharmacokinetic profiles.
• Agrochemical Synthesis: Employed as a building block for creating new generations of pesticides and herbicides, leveraging its heterocyclic structure.
• Chemical Biology Probes: Utilized in the development of molecular probes for studying enzyme function and biological pathways in academic and industrial research settings.
• Custom Synthesis & Contract Manufacturing: A vital starting material for fine chemical manufacturers offering bespoke synthesis services to the life sciences industry.

Basic Information

Product Name	2-Pyridinamine, 6-Chloro-3-Nitro-n-(Tetrahydro-2H-Pyran-4-Yl)-
CAS No.	1153383-94-8
Molecular Formula	C10H12ClN3O3
Molecular Weight	257.67 g/mol
Synonyms	6-Chloro-3-nitro-N-(tetrahydro-2H-pyran-4-yl)pyridin-2-amine; N-(Tetrahydro-2H-pyran-4-yl)-6-chloro-3-nitropyridin-2-amine; 2-Amino-6-chloro-3-nitropyridine, N-tetrahydropyran-4-yl derivative; 1153383-94-8; 6-Chloro-3-nitro-N-(oxan-4-yl)pyridin-2-amine; (6-Chloro-3-nitro-2-pyridinyl)(tetrahydro-2H-pyran-4-yl)amine
EINECS	Contact for details

Quality Control

Our production of 2-Pyridinamine, 6-Chloro-3-Nitro-n-(Tetrahydro-2H-Pyran-4-Yl)- adheres to stringent quality management protocols to ensure batch-to-batch consistency and high purity, essential for sensitive pharmaceutical R&D. All materials are characterized and released against comprehensive specifications. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). Keep away from incompatible materials. For long-term storage, consider an inert atmosphere to preserve stability.

Specification

Item	Specification
Appearance	Yellow to light brown crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.