Description

4-Bromo-N,n-Dimethylpicolinamide is a high-purity brominated picolinamide derivative, serving as a critical synthetic intermediate in advanced organic chemistry. Its value lies in its versatile reactivity, particularly in cross-coupling reactions and as a building block for complex heterocyclic systems. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and material science industries who require reliable, high-quality intermediates for developing new active ingredients and functional molecules.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel active pharmaceutical ingredients (APIs), particularly for kinase inhibitors and other small-molecule therapeutics.
• Agrochemical Synthesis: Used in the research and development of new herbicides, fungicides, and plant growth regulators.
• Material Science Precursor: Employed in the creation of specialized ligands for catalysis and in the development of organic electronic materials.
• Cross-Coupling Reactions: Serves as a versatile substrate in Suzuki, Buchwald-Hartwig, and other palladium-catalyzed coupling reactions to form complex biaryl structures.
• Chemical Research & Development: A valuable reagent for academic and industrial R&D laboratories exploring new synthetic methodologies and heterocyclic chemistry.
• Ligand Synthesis: Used as a precursor for constructing sophisticated chelating agents and catalysts in asymmetric synthesis.

Basic Information

Product Name	4-Bromo-N,n-Dimethylpicolinamide
CAS No.	1153327-12-8
Molecular Formula	C8H9BrN2O
Molecular Weight	229.08 g/mol
Synonyms	4-Bromo-N,N-dimethylpyridine-2-carboxamide; 2-Pyridinecarboxamide, 4-bromo-N,N-dimethyl-; N,N-Dimethyl-4-bromopicolinamide; 4-Bromo-2-(dimethylcarbamoyl)pyridine; 4-Bromopicolinic acid dimethylamide; Picolinamide, 4-bromo-N,N-dimethyl-; 1153327-12-8
EINECS	Contact for details

Quality Control

Our 4-Bromo-N,n-Dimethylpicolinamide is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment to guarantee it meets the stringent requirements for research and production applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (typically 15-25°C). Keep away from incompatible materials. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.